EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.108 | additional information | high osmolarity induces the enzyme expression, requirements | Virgibacillus pantothenticus | |
4.2.1.108 | additional information | high osmolarity induces the enzyme expression, requirements | Alkalihalobacillus alcalophilus | |
4.2.1.108 | additional information | high osmolarity induces the enzyme expression, requirements | Sporosarcina psychrophila | |
4.2.1.108 | additional information | high osmolarity induces the enzyme expression, requirements | Sporosarcina pasteurii | |
4.2.1.108 | additional information | high osmolarity induces the enzyme expression, requirements | Virgibacillus salexigens | |
4.2.1.108 | additional information | high osmolarity induces the enzyme expression, requirements | Chromohalobacter salexigens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.178 | - |
Sporosarcina pasteurii |
4.2.1.108 | gene ectC encoded in the ectABC gene cluster, functional expression in Escherichia coli | Chromohalobacter salexigens |
4.2.1.108 | gene ectC, encoded in the ectABC gene cluster, sequence determination and analysis, phylogenetic analysis, DNA sequence comparison, expression in Escherichia coli | Sporosarcina pasteurii |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.108 | NaCl | required for activity | Sporosarcina pasteurii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.178 | acetyl-CoA + L-2,4-diaminobutanoate | Sporosarcina pasteurii | together EctA, EctB and EctC constitute the ectoine biosynthetic pathway. ectABC genes are genetically organized as an operon whose expression is strongly enhanced when the osmolarity of the growth medium is raised | CoA + N4-acetyl-L-2,4-diaminobutanoate | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | Virgibacillus pantothenticus | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | Alkalihalobacillus alcalophilus | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | Sporosarcina psychrophila | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | Sporosarcina pasteurii | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | Virgibacillus salexigens | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | Chromohalobacter salexigens | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | L-ectoine + H2O | - |
? | |
4.2.1.108 | additional information | Virgibacillus pantothenticus | phylogenetic analysis | ? | - |
? | |
4.2.1.108 | additional information | Alkalihalobacillus alcalophilus | phylogenetic analysis | ? | - |
? | |
4.2.1.108 | additional information | Sporosarcina psychrophila | phylogenetic analysis | ? | - |
? | |
4.2.1.108 | additional information | Sporosarcina pasteurii | phylogenetic analysis | ? | - |
? | |
4.2.1.108 | additional information | Virgibacillus salexigens | phylogenetic analysis | ? | - |
? | |
4.2.1.108 | additional information | Chromohalobacter salexigens | phylogenetic analysis | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.178 | Sporosarcina pasteurii | - |
- |
- |
4.2.1.108 | Alkalihalobacillus alcalophilus | - |
strain DSM 485 | - |
4.2.1.108 | Chromohalobacter salexigens | Q9ZEU6 | formerly Halomonas elongata, strain DSM 3043, gene ectC encoded in the ectABC gene cluster | - |
4.2.1.108 | no activity in Aneurinibacillus aneurinilyticus | - |
formerly Bacillus aneurinilyticus | - |
4.2.1.108 | no activity in Aneurinibacillus aneurinilyticus DSM 5562 | - |
formerly Bacillus aneurinilyticus | - |
4.2.1.108 | no activity in Bacillus cereus | - |
strain DSM31 | - |
4.2.1.108 | no activity in Bacillus cereus DSM 31 | - |
strain DSM31 | - |
4.2.1.108 | no activity in Bacillus circulans | - |
strain DSM 9 | - |
4.2.1.108 | no activity in Bacillus licheniformis | - |
strain DSM 13 | - |
4.2.1.108 | no activity in Bacillus megaterium | - |
strain DSM 32 | - |
4.2.1.108 | no activity in Bacillus subtilis | - |
- |
- |
4.2.1.108 | no activity in Bacillus subtilis JH642 | - |
- |
- |
4.2.1.108 | no activity in Bacillus thuringiensis | - |
strain DSM 2046 | - |
4.2.1.108 | no activity in Paenibacillus polymyxa | - |
strain DSM 36 | - |
4.2.1.108 | Sporosarcina pasteurii | Q9AP33 | strain DSM 33, gene ectC encoded in the ectABC gene cluster | - |
4.2.1.108 | Sporosarcina psychrophila | - |
formerly Bacillus psychrophilus, strain DSM 3 | - |
4.2.1.108 | Virgibacillus pantothenticus | - |
formerl Bacillus pantothenticus, strain DSM 26 | - |
4.2.1.108 | Virgibacillus salexigens | - |
formerly Bacillus salexigens, strain DSM 11438 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.178 | acetyl-CoA + L-2,4-diaminobutanoate | together EctA, EctB and EctC constitute the ectoine biosynthetic pathway. ectABC genes are genetically organized as an operon whose expression is strongly enhanced when the osmolarity of the growth medium is raised | Sporosarcina pasteurii | CoA + N4-acetyl-L-2,4-diaminobutanoate | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | Virgibacillus pantothenticus | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | Alkalihalobacillus alcalophilus | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | Sporosarcina psychrophila | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | Sporosarcina pasteurii | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | Virgibacillus salexigens | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant | Chromohalobacter salexigens | L-ectoine + H2O | - |
? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid | Sporosarcina psychrophila | L-ectoine + H2O | NMR identification | ? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid | Sporosarcina pasteurii | L-ectoine + H2O | NMR identification | ? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid | Virgibacillus pantothenticus | L-ectoine + H2O | NMR product identification | ? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid | Alkalihalobacillus alcalophilus | L-ectoine + H2O | NMR product identification | ? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid | Virgibacillus salexigens | L-ectoine + H2O | NMR product identification | ? | |
4.2.1.108 | 4-N-acetyl-L-2,4-diaminobutanoate | i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid | Chromohalobacter salexigens | L-ectoine + H2O | NMR product identification | ? | |
4.2.1.108 | additional information | phylogenetic analysis | Virgibacillus pantothenticus | ? | - |
? | |
4.2.1.108 | additional information | phylogenetic analysis | Alkalihalobacillus alcalophilus | ? | - |
? | |
4.2.1.108 | additional information | phylogenetic analysis | Sporosarcina psychrophila | ? | - |
? | |
4.2.1.108 | additional information | phylogenetic analysis | Sporosarcina pasteurii | ? | - |
? | |
4.2.1.108 | additional information | phylogenetic analysis | Virgibacillus salexigens | ? | - |
? | |
4.2.1.108 | additional information | phylogenetic analysis | Chromohalobacter salexigens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.178 | EctA | - |
Sporosarcina pasteurii |