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Literature summary extracted from

  • Hui, C.S.; Kuo, H.M.; Yu, C.S.; Li, T.M.
    Evidence for arylamine N-acetyltransferase activity in Klebsiella pneumoniae (2004), J. Microbiol. Immunol. Infect., 37, 208-215.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.5 Cu2+
-
 Klebsiella pneumoniae
2.3.1.5 iodoacetamide 50% inhibition at 0.25 mM, 90% inhibition at 1.0 mM Klebsiella pneumoniae
2.3.1.5 Zn2+
-
 Klebsiella pneumoniae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.5 2.42
-
 4-Aminobenzoate
-
 Klebsiella pneumoniae
2.3.1.5 2.92
-
 2-Aminofluorene
-
 Klebsiella pneumoniae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.5 cytosol
-
 Klebsiella pneumoniae 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.5 44900
-
 x * 44900, SDS-PAGE Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.5 additional information Klebsiella pneumoniae no expression of NAT2 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.5 Klebsiella pneumoniae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.5 partial Klebsiella pneumoniae

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.5 3.506
-
-
 Klebsiella pneumoniae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.5 acetyl-CoA + 2-aminofluorene
-
 Klebsiella pneumoniae CoA + 2-acetylaminofluorene
-
 ?
2.3.1.5 acetyl-CoA + 4-aminobenzoate
-
 Klebsiella pneumoniae CoA + 4-acetylaminobenzoate
-
 ?
2.3.1.5 additional information no expression of NAT2 Klebsiella pneumoniae ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.5 ? x * 44900, SDS-PAGE Klebsiella pneumoniae

Synonyms

EC Number Synonyms Comment Organism
2.3.1.5 NAT1
-
 Klebsiella pneumoniae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.5 37
-
 activity with 2-aminofluorene and 4-aminobenzoate Klebsiella pneumoniae

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.3.1.5 4 60 the enzyme is active in the range Klebsiella pneumoniae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.5 7
-
 activity with 2-aminofluorene and 4-aminobenzoate Klebsiella pneumoniae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.5 5 9.5 about 25% of maximal activity pH 5.0 and pH 9.5 with 2-aminofluorene as substrate, about 65% of maximal activity at pH 5.0 and at pH 9.5 with p-aminobenzoate as substrate Klebsiella pneumoniae