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Literature summary extracted from

  • Solaas, K.; Ulvestad, A.; Soreide, O.; Kase, B.F.
    Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts (2000), J. Lipid Res., 41, 1154-1162.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.2.27 additional information
-
 additional information kinetics Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.27 cytosol high activity Homo sapiens 5829
-
3.1.2.27 microsome
-
 Homo sapiens
-
-
3.1.2.27 mitochondrion especially in the light mitochondrial fraction Homo sapiens 5739
-
3.1.2.27 additional information subcellular distribution, overview Homo sapiens
-
-
3.1.2.27 nucleus
-
 Homo sapiens 5634
-
3.1.2.27 peroxisome highest enzyme activity Homo sapiens 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.27 chenodeoxycholoyl-CoA + H2O Homo sapiens
-
 chenodeoxycholate + CoA
-
 ?
3.1.2.27 choloyl-CoA + H2O Homo sapiens
-
 cholate + CoA
-
 ?
3.1.2.27 additional information Homo sapiens enzyme is involved in the regulation of free to conjugated bile acid ratio, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.27 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.2.27 partially, subcellular fractionation Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.27 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.2.27 0.0014 0.0031 subcellular fractions, overview Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.27 chenodeoxycholoyl-CoA + H2O
-
 Homo sapiens chenodeoxycholate + CoA
-
 ?
3.1.2.27 choloyl-CoA + H2O
-
 Homo sapiens cholate + CoA
-
 ?
3.1.2.27 additional information enzyme is involved in the regulation of free to conjugated bile acid ratio, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.2.27 bile acid-CoA thioesterase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.2.27 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.2.27 8
-
 assay at Homo sapiens