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Literature summary extracted from

  • Ghibaudi, E.; Laurenti, E.; Pacchiardo, C.; Suriano, G.; Moguilevsky, N.; Pia Ferrari, R.
    Organic and inorganic substrates as probes for comparing native bovine lactoperoxidase and recombinant human myeloperoxidase (2003), J. Inorg. Biochem., 94, 146-154.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.2.2 expression in CHO cells Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.2.2 0.25
-
 SCN- 25°C, pH 5.5 Homo sapiens
1.11.2.2 0.29
-
 SCN- 25°C, pH 5.5 Bos taurus
1.11.2.2 0.52
-
 3,4-dihydroxyphenylacetic acid 25°C, pH 5.5 Bos taurus
1.11.2.2 0.64
-
 dopamine 25°C, pH 5.5 Homo sapiens
1.11.2.2 1.84
-
 catechol 25°C, pH 5.5 Bos taurus
1.11.2.2 21.1
-
 catechol 25°C, pH 5.5 Homo sapiens
1.11.2.2 21.9
-
 3,4-dihydroxyphenylacetic acid 25°C, pH 5.5 Homo sapiens
1.11.2.2 136.3
-
 dopamine 25°C, pH 5.5 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.11.2.2 Bos taurus
-
-
-
1.11.2.2 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.11.2.2 purified from raw milk Bos taurus
1.11.2.2 recombinant MPO Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.2.2 mammary gland
-
 Bos taurus
-
1.11.2.2 neutrophil neutrophilic granulocytes Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.2.2 3,4-dihydroxyphenylacetic acid + H2O2
-
 Homo sapiens ? + H2O
-
 ?
1.11.2.2 3,4-dihydroxyphenylacetic acid + H2O2
-
 Bos taurus ? + H2O
-
 ?
1.11.2.2 catechol + H2O2
-
 Homo sapiens ? + H2O
-
 ?
1.11.2.2 catechol + H2O2
-
 Bos taurus ? + H2O
-
 ?
1.11.2.2 dopamine + H2O2
-
 Homo sapiens ? + H2O
-
 ?
1.11.2.2 dopamine + H2O2
-
 Bos taurus ? + H2O
-
 ?
1.11.2.2 SCN- + H2O2
-
 Homo sapiens OSCN- + H2O
-
 ?
1.11.2.2 SCN- + H2O2
-
 Bos taurus OSCN- + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.2.2 LPO
-
 Bos taurus
1.11.2.2 recombinant human MPO
-
 Homo sapiens
1.11.2.2 rhMPO
-
 Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.11.2.2 0.0000001
-
 dopamine 25°C, pH 5.5 Homo sapiens
1.11.2.2 0.00000016
-
 SCN- 25°C, pH 5.5 Homo sapiens
1.11.2.2 0.0000016
-
 dopamine 25°C, pH 5.5 Bos taurus
1.11.2.2 0.0000033
-
 SCN- 25°C, pH 5.5 Bos taurus
1.11.2.2 0.000012
-
 catechol 25°C, pH 5.5 Homo sapiens
1.11.2.2 0.000022
-
 catechol 25°C, pH 5.5 Bos taurus