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Literature summary extracted from
- Up-regulation of human myo-inositol oxygenase by hyperosmotic stress in renal proximal tubular epithelial cells (2005), J. Biol. Chem., 280, 19895-19901.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.13.99.1 | expression in epithelial cell line LLC-PK1 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.99.1 | myo-inositol + O2 | Homo sapiens | - |
D-glucuronic acid + H2O | - |
ir |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.99.1 | Homo sapiens | Q9UGB7 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.13.99.1 | kidney | MIOX expression is upregulated by hyperosmolarity, particularly by polyols like mannitol, sorbitol and xylitol | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.99.1 | myo-inositol + O2 | - |
Homo sapiens | D-glucuronic acid + H2O | - |
ir | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.13.99.1 | MIOX | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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