EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.3.10 | expression in Escherichia coli | Staphylococcus aureus |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.3.3.10 | sitting-drop vapour-diffusion method, crystal strcuture of full-length enzyme expressed in Escherichia coli is determined at 2.0 A resolution, crystal structure of HMG-CoA synthase with acetoacetyl-CoA is determined at 2.5 A resolution | Staphylococcus aureus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | Staphylococcus aureus | the enzyme catalyzes the first committed step in the mevalonate pathway | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.3.10 | Staphylococcus aureus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.3.10 | recombinant | Staphylococcus aureus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | - |
Staphylococcus aureus | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
? | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | the enzyme catalyzes the first committed step in the mevalonate pathway | Staphylococcus aureus | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.3.10 | dimer | - |
Staphylococcus aureus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.3.10 | 3-hydroxy-3-methylglutaryl-CoA synthase | - |
Staphylococcus aureus |
2.3.3.10 | HMG-CoS synthase | - |
Staphylococcus aureus |