EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.3.13 | L-leucine | linear, non-competitive feedback inhibition | Mycobacterium tuberculosis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.13 | acetyl-CoA + alpha-ketoisovalerate + H2O | Mycobacterium tuberculosis | first step of leucine biosynthesis | alpha-isopropylmalate + CoA | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.3.13 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.13 | acetyl-CoA + alpha-ketoisovalerate + H2O | first step of leucine biosynthesis | Mycobacterium tuberculosis | alpha-isopropylmalate + CoA | - |
? | |
2.3.3.13 | acetyl-CoA + alpha-ketoisovalerate + H2O | aldol condensation reaction | Mycobacterium tuberculosis | alpha-isopropylmalate + CoA | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.3.13 | 0.017 | - |
L-leucine | - |
Mycobacterium tuberculosis |