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Literature summary extracted from

  • Haines, N.; Irvine, K.D.
    Functional analysis of Drosophila beta1,4-N-acetylgalactosaminyltransferases (2005), Glycobiology, 15, 335-346.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.244 full-length cDNA is cloned into vectors for expression in cultured Drosophila S2 Drosophila melanogaster

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.92 additional information isoform betaGalNAcTA null mutants are viable and fertile, but display behavioral phenotypes suggesting roles of enzyme in neuronal and/or muscle function. Isoform betaGalNAcTB null mutants are viable and show no evident morphological or behavioral phenotype. Double mutants display only the phenotypes associated with mutation of betaGalNAcTA Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.244 additional information Drosophila melanogaster flies mutant for beta4GalNAcTA are viable and fertile but display behavioral phenotypes suggestive of essential roles for GalNAc-beta1,4-GlcNAc containing glycoconjugates in neuronal and/or muscular function ?
-
 ?
2.4.1.244 additional information Drosophila melanogaster flies mutant for beta4GalNAcTB are viable and display no evident morphological or behavioral phenotypes ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.92 Drosophila melanogaster
-
 isoforms betaGalNAcTA and betaGalNAcTB
-
2.4.1.244 Drosophila melanogaster
-
-
-
2.4.1.244 Drosophila melanogaster Q7KN92
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.244 additional information flies mutant for beta4GalNAcTA are viable and fertile but display behavioral phenotypes suggestive of essential roles for GalNAc-beta1,4-GlcNAc containing glycoconjugates in neuronal and/or muscular function Drosophila melanogaster ?
-
 ?
2.4.1.244 additional information flies mutant for beta4GalNAcTB are viable and display no evident morphological or behavioral phenotypes Drosophila melanogaster ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.244 beta4GalNAcTA
-
 Drosophila melanogaster
2.4.1.244 beta4GalNAcTB
-
 Drosophila melanogaster