Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chen, T.L.; Chen, C.; Bergeron, N.Q.; Close, B.E.; Bohrer, T.J.; Vertel, B.M.; Colley, K.J.
    The two rat alpha 2,6-sialyltransferase (ST6Gal I) isoforms: evaluation of catalytic activity and intra-Golgi localization (2003), Glycobiology, 13, 109-117.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.3.1 isoform STcys expressed in CHO cells or in HeLa cells Rattus norvegicus
2.4.3.1 isoform STtyr expressed in CHO cells or in HeLa cells Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.3.1 0.147
-
 asialo-alpha1-acid glycoprotein
-
 Rattus norvegicus
2.4.3.1 0.163
-
 asialo-alpha1-acid glycoprotein
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.1 endoplasmic reticulum
-
 Rattus norvegicus 5783
-
2.4.3.1 endoplasmic reticulum isoform Stcys is found in both the endoplasmic reticulum and in Golgi Rattus norvegicus 5783
-
2.4.3.1 Golgi vesicle in medial-trans regions. Isoform Stcys is found in both the endoplasmic reticulum and in Golgi Rattus norvegicus
-
-
2.4.3.1 Golgi vesicle in medial-trans regions. Isoform STtyr is restricted to Golgi in most cells Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.3.1 additional information Rattus norvegicus the enzyme functions in Golgi vesicles to terminally sialylate the N-linked oligosaccharides of glycoproteins ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Rattus norvegicus
-
 isoform STcys
-
2.4.3.1 Rattus norvegicus
-
 isoform STtyr
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.3.1 isoform STcys Rattus norvegicus
2.4.3.1 isoform STtyr Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-9-O-acetyl-N-acetylneuraminate + asialo-alpha1-acid glycoprotein
-
 Rattus norvegicus CMP + ?
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + asialo-fetuin recombinant isoform STcys is somewhat more active then the recombinant isoform STtyr Rattus norvegicus CMP + fetuin
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + asialo-transferrin
-
 Rattus norvegicus CMP + transferrin
-
 ?
2.4.3.1 additional information the enzyme functions in Golgi vesicles to terminally sialylate the N-linked oligosaccharides of glycoproteins Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.1 alpha 2,6-sialyltransferase
-
 Rattus norvegicus
2.4.3.1 ST6Gal I
-
 Rattus norvegicus