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Literature summary extracted from

  • Giles, S.S.; Perfect, J.R.; Cox, G.M.
    Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans (2005), Fungal Genet. Biol., 42, 20-29.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.11.1.5 additional information disruption and deletion mutants show intracellular growth defects in macrophage like cells in vitro. The enzyme provides protection against oxidative stress within macrophages in vitro Cryptococcus neoformans

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.11.1.5 H2O2 at a concentration of 8% and 16% can inhibit the growth of wild-type strain H99 Cryptococcus neoformans

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.11.1.5 mitochondrion
-
 Cryptococcus neoformans 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.5 ferrocytochrome c + H2O2 Cryptococcus neoformans
-
 ferricytochrome c + H2O
-
 ?
1.11.1.5 ferrocytochrome c + H2O2 Cryptococcus neoformans H99
-
 ferricytochrome c + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.5 Cryptococcus neoformans Q6URB0
-
-
1.11.1.5 Cryptococcus neoformans H99 Q6URB0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.5 ferrocytochrome c + H2O2
-
 Cryptococcus neoformans ferricytochrome c + H2O
-
 ?
1.11.1.5 ferrocytochrome c + H2O2 antioxidant defense Cryptococcus neoformans ferricytochrome c + H2O
-
 ?
1.11.1.5 ferrocytochrome c + H2O2
-
 Cryptococcus neoformans H99 ferricytochrome c + H2O
-
 ?
1.11.1.5 ferrocytochrome c + H2O2 antioxidant defense Cryptococcus neoformans H99 ferricytochrome c + H2O
-
 ?