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Literature summary extracted from

  • Achkor, H.; Diaz, M.; Fernandez, M.R.; Biosca, J.A.; Pares, X.; Martinez, M.C.
    Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis (2003), Plant Physiol., 132, 2248-2255.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.284 overexpression in Saccharomyces cerevisiae Arabidopsis thaliana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.284 0.003
-
farnesol pH 10, 25°C Arabidopsis thaliana
1.1.1.284 0.007
-
S-hydroxymethylglutathione pH 8, 25°C Arabidopsis thaliana
1.1.1.284 0.0077
-
farnesol pH 7.5, 25°C Arabidopsis thaliana
1.1.1.284 0.8
-
geraniol pH 10, 25°C Arabidopsis thaliana
1.1.1.284 3.5
-
cinnamyl alcohol pH 10, 25°C Arabidopsis thaliana
1.1.1.284 4.7
-
12-Hydroxydodecanoic acid pH 10, 25°C Arabidopsis thaliana
1.1.1.284 22
-
cinnamyl alcohol pH 7.5, 25°C Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.284 S-(hydroxymethyl)glutathione + NAD+ Arabidopsis thaliana essential role in formaldehyde detoxifcation S-formylglutathione + NADH + H+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.284 Arabidopsis thaliana
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.284
-
Arabidopsis thaliana

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.284 15
-
-
Arabidopsis thaliana

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.284 12-hydroxydodecanoic acid + glutathione + NAD+
-
Arabidopsis thaliana S-(11-carboxy)undecanylglutathione + NADH
-
?
1.1.1.284 cinnamyl alcohol + glutathione + NAD+
-
Arabidopsis thaliana S-cinnamylglutathione + NADH
-
?
1.1.1.284 farnesol + glutathione + NAD+
-
Arabidopsis thaliana S-farnesylglutathione + NADH
-
?
1.1.1.284 geraniol + glutathione + NAD+
-
Arabidopsis thaliana S-geranylglutathione + NADH
-
?
1.1.1.284 S-(hydroxymethyl)glutathione + NAD+
-
Arabidopsis thaliana S-formylglutathione + NADH + H+
-
?
1.1.1.284 S-(hydroxymethyl)glutathione + NAD+ essential role in formaldehyde detoxifcation Arabidopsis thaliana S-formylglutathione + NADH + H+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.284 FALDH
-
Arabidopsis thaliana
1.1.1.284 Glutathione-dependent formaldehyde dehydrogenase
-
Arabidopsis thaliana

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.284 0.1
-
farnesol pH 7.5, 25°C Arabidopsis thaliana
1.1.1.284 2.1
-
farnesol pH 10, 25°C Arabidopsis thaliana
1.1.1.284 5.4
-
cinnamyl alcohol pH 7.5, 25°C Arabidopsis thaliana
1.1.1.284 5.6
-
12-Hydroxydodecanoic acid pH 10, 25°C Arabidopsis thaliana
1.1.1.284 20
-
geraniol pH 10, 25°C Arabidopsis thaliana
1.1.1.284 20.33
-
cinnamyl alcohol pH 10, 25°C Arabidopsis thaliana
1.1.1.284 22.5
-
S-(hydroxymethyl)glutathione pH 8, 25°C Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.284 NAD+
-
Arabidopsis thaliana