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Literature summary extracted from

  • Winzer, K.; Hardie, K.R.; Burgess, N.; Doherty, N.; Kirke, D.; Holden, M.T.; Linforth, R.; Cornell, K.A.; Taylor, A.J.; Hill, P.J.; Williams, P.
    LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone (2002), Microbiology, 148, 909-922.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.21 S-ribosylhomocysteine Staphylococcus aureus the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine Escherichia coli the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine Neisseria meningitidis the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine Porphyromonas gingivalis the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.21 Escherichia coli
-
-
-
4.4.1.21 Neisseria meningitidis
-
-
-
4.4.1.21 no activity in Pseudomonas aeruginosa
-
-
-
4.4.1.21 Porphyromonas gingivalis
-
-
-
4.4.1.21 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.21 S-ribosylhomocysteine
-
 Staphylococcus aureus L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine
-
 Escherichia coli L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine
-
 Neisseria meningitidis L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine
-
 Porphyromonas gingivalis L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine Staphylococcus aureus L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine Escherichia coli L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine Neisseria meningitidis L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?
4.4.1.21 S-ribosylhomocysteine the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine Porphyromonas gingivalis L-homocysteine + 4,5-dihydroxy-2,3-pentanedione
-
 ?