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Literature summary extracted from

  • Nakagawa, J.; Ishikura, S.; Asami, J.; Isaji, T.; Usami, N.; Hara, A.; Sakurai, T.; Tsuritani, K.; Oda, K.; Takahashi, M.; Yoshimoto, M.; Otsuka, N.; Kitamura, K.
    Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney (2002), J. Biol. Chem., 277, 17888-17891.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.10 DNA sequence determination and analysis, expression in Escherichia coli strain BL21(DE3) Cavia porcellus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.10 3-hydroxybutyric acid 50% inhibition at 1.1 mM Homo sapiens
1.1.1.10 3-hydroxybutyric acid 50% inhibition at 1.0 mM Mesocricetus auratus
1.1.1.10 3-hydroxybutyric acid 50% inhibition at 2.0 mM Rattus norvegicus
1.1.1.10 acetoacetic acid 50% inhibition at 0.63 mM Homo sapiens
1.1.1.10 acetoacetic acid 50% inhibition at 1.8 mM Mesocricetus auratus
1.1.1.10 acetoacetic acid 50% inhibition at 2.5 mM Rattus norvegicus
1.1.1.10 heptanoic acid 50% inhibition at 0.38 mM Homo sapiens
1.1.1.10 heptanoic acid 50% inhibition at 1.4 mM Mesocricetus auratus
1.1.1.10 heptanoic acid 50% inhibition at 2.0 mM Mus musculus
1.1.1.10 heptanoic acid 50% inhibition at 2.5 mM Rattus norvegicus
1.1.1.10 hexanoic acid 50% inhibition at 0.10 mM Homo sapiens
1.1.1.10 hexanoic acid 50% inhibition at 0.40 mM Mesocricetus auratus
1.1.1.10 hexanoic acid 50% inhibition at 1.1 mM Mus musculus
1.1.1.10 hexanoic acid 50% inhibition at 0.42 mM Rattus norvegicus
1.1.1.10 additional information acetic acid, threonic acid, and octanoic acid are poor inhibitors Homo sapiens
1.1.1.10 additional information acetic acid is a poor inhibitor Mesocricetus auratus
1.1.1.10 additional information acetic acid, acetoacetic acid, 3-OH-butyric acid, and octanoic acid are poor inhibitors Mus musculus
1.1.1.10 additional information acetic acid, oxaloacetic acid, and octanoic acid are poor inhibitors Rattus norvegicus
1.1.1.10 n-butyric acid 50% inhibition at 0.064 mM Homo sapiens
1.1.1.10 n-butyric acid 50% inhibition at 0.026 mM Mesocricetus auratus
1.1.1.10 n-butyric acid 50% inhibition at 0.05 mM Mus musculus
1.1.1.10 n-butyric acid 50% inhibition at 0.052 mM Rattus norvegicus
1.1.1.10 octanoic acid 50% inhibition at 2.5 mM Mesocricetus auratus
1.1.1.10 oxaloacetic acid 50% inhibition at 0.91 mM Homo sapiens
1.1.1.10 oxaloacetic acid 50% inhibition at 2.5 mM Mesocricetus auratus
1.1.1.10 oxaloacetic acid 50% inhibition at 2.5 mM Mus musculus
1.1.1.10 pentanoic acid 50% inhibition at 0.15 mM Homo sapiens
1.1.1.10 pentanoic acid 50% inhibition at 0.20 mM Mesocricetus auratus
1.1.1.10 pentanoic acid 50% inhibition at 0.38 mM Mus musculus
1.1.1.10 pentanoic acid 50% inhibition at 0.5 mM Rattus norvegicus
1.1.1.10 propionic acid 50% inhibition at 0.38 mM Homo sapiens
1.1.1.10 propionic acid 50% inhibition at 0.096 mM Mesocricetus auratus
1.1.1.10 propionic acid 50% inhibition at 0.17 mM Mus musculus
1.1.1.10 propionic acid 50% inhibition at 0.13 mM Rattus norvegicus
1.1.1.10 Pyruvic acid 50% inhibition at 0.50 mM Homo sapiens
1.1.1.10 Pyruvic acid 50% inhibition at 0.88 mM Mesocricetus auratus
1.1.1.10 Pyruvic acid 50% inhibition at 1.5 mM Mus musculus
1.1.1.10 Pyruvic acid 50% inhibition at 1.0 mM Rattus norvegicus
1.1.1.10 threonic acid 50% inhibition at 0.75 mM Mesocricetus auratus
1.1.1.10 threonic acid 50% inhibition at 1.5 mM Mus musculus
1.1.1.10 threonic acid 50% inhibition at 1.9 mM Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.10 0.001
-
 NADP+ pH 7.0, 25°C Homo sapiens
1.1.1.10 0.002
-
 NADPH pH 7.0, 25°C Homo sapiens
1.1.1.10 0.002
-
 NADP+ pH 7.0, 25°C Cavia porcellus
1.1.1.10 0.003
-
 NADPH pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 0.003
-
 NADP+ pH 7.0, 25°C Mus musculus
1.1.1.10 0.003
-
 NADP+ pH 7.0, 25°C Rattus norvegicus
1.1.1.10 0.003
-
 NADP+ pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 0.005
-
 NADPH pH 7.0, 25°C Mus musculus
1.1.1.10 0.005
-
 NADPH pH 7.0, 25°C Cavia porcellus
1.1.1.10 0.007
-
 NADPH pH 7.0, 25°C Rattus norvegicus
1.1.1.10 0.05
-
 L-xylulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 0.077
-
 diacetyl pH 7.0, 25°C Homo sapiens
1.1.1.10 0.12
-
 NADH pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 0.17
-
 NADH pH 7.0, 25°C Homo sapiens
1.1.1.10 0.2
-
 diacetyl pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 0.21
-
 L-xylulose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.22
-
 NADH pH 7.0, 25°C Mus musculus
1.1.1.10 0.23
-
 L-xylulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 0.24
-
 L-xylulose pH 7.0, 25°C Mus musculus
1.1.1.10 0.26
-
 L-xylulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 0.36
-
 NADH pH 7.0, 25°C Rattus norvegicus
1.1.1.10 0.52
-
 diacetyl pH 7.0, 25°C Cavia porcellus
1.1.1.10 0.59
-
 D-erythrose pH 7.0, 25°C Cavia porcellus
1.1.1.10 0.67
-
 diacetyl pH 7.0, 25°C Mus musculus
1.1.1.10 0.69
-
 NADH pH 7.0, 25°C Cavia porcellus
1.1.1.10 0.85
-
 NAD+ pH 7.0, 25°C Homo sapiens
1.1.1.10 0.91
-
 NAD+ pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 0.99
-
 NAD+ pH 7.0, 25°C Mus musculus
1.1.1.10 1.1
-
 diacetyl pH 7.0, 25°C Rattus norvegicus
1.1.1.10 1.2
-
 DL-glyceraldehyde pH 7.0, 25°C Homo sapiens
1.1.1.10 1.4
-
 DL-glyceraldehyde pH 7.0, 25°C Cavia porcellus
1.1.1.10 1.5
-
 NAD+ pH 7.0, 25°C Rattus norvegicus
1.1.1.10 1.5
-
 acetoin pH 7.0, 25°C Homo sapiens
1.1.1.10 1.6
-
 dihydroxyacetone pH 7.0, 25°C Homo sapiens
1.1.1.10 1.9
-
 D-threose pH 7.0, 25°C Homo sapiens
1.1.1.10 2
-
 L-erythrulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 2
-
 D-threose pH 7.0, 25°C Cavia porcellus
1.1.1.10 2.4
-
 D-erythrose pH 7.0, 25°C Homo sapiens
1.1.1.10 2.4
-
 D-threose pH 7.0, 25°C Mus musculus
1.1.1.10 2.5
-
 L-erythrulose pH 7.0, 25°C Homo sapiens
1.1.1.10 2.7
-
 DL-glyceraldehyde pH 7.0, 25°C Rattus norvegicus
1.1.1.10 2.7
-
 D-threose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 2.9
-
 L-erythrulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 2.9
-
 L-threose pH 7.0, 25°C Cavia porcellus
1.1.1.10 3.3
-
 acetoin pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 3.9
-
 D-erythrose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 4
-
 D-threose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 4.2
-
 L-threose pH 7.0, 25°C Homo sapiens
1.1.1.10 4.3
-
 L-threose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 4.8
-
 D-xylulose pH 7.0, 25°C Homo sapiens
1.1.1.10 4.8
-
 L-erythrulose pH 7.0, 25°C Mus musculus
1.1.1.10 5
-
 D-ribulose pH 7.0, 25°C Homo sapiens
1.1.1.10 5.1
-
 DL-glyceraldehyde pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 5.5
-
 L-erythrulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 5.6
-
 L-threose pH 7.0, 25°C Mus musculus
1.1.1.10 5.7
-
 D-ribulose pH 7.0, 25°C Mus musculus
1.1.1.10 5.7
-
 D-erythrose pH 7.0, 25°C Mus musculus
1.1.1.10 6
-
 DL-glyceraldehyde pH 7.0, 25°C Mus musculus
1.1.1.10 6
-
 D-erythrose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 6.3
-
 D-ribulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 6.3
-
 D-ribulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 6.9
-
 acetoin pH 7.0, 25°C Rattus norvegicus
1.1.1.10 7.8
-
 D-ribulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 8.3
-
 L-threose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 9
-
 acetoin pH 7.0, 25°C Mus musculus
1.1.1.10 10
-
 xylitol pH 7.0, 25°C Cavia porcellus
1.1.1.10 11
-
 xylitol pH 7.0, 25°C Rattus norvegicus
1.1.1.10 12
-
 D-xylulose pH 7.0, 25°C Mus musculus
1.1.1.10 12
-
 D-xylulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 13
-
 acetoin pH 7.0, 25°C Cavia porcellus
1.1.1.10 14
-
 D-threitol pH 7.0, 25°C Cavia porcellus
1.1.1.10 15
-
 xylitol pH 7.0, 25°C Mus musculus
1.1.1.10 16
-
 D-threitol pH 7.0, 25°C Rattus norvegicus
1.1.1.10 18
-
 D-xylulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 18
-
 D-xylulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 18
-
 D-threitol pH 7.0, 25°C Homo sapiens
1.1.1.10 25
-
 xylitol pH 7.0, 25°C Homo sapiens
1.1.1.10 34
-
 D-threitol pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 36
-
 dihydroxyacetone pH 7.0, 25°C Cavia porcellus
1.1.1.10 37
-
 D-threitol pH 7.0, 25°C Mus musculus
1.1.1.10 40
-
 xylitol pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 47
-
 dihydroxyacetone pH 7.0, 25°C Mus musculus
1.1.1.10 60
-
 dihydroxyacetone pH 7.0, 25°C Rattus norvegicus
1.1.1.10 60
-
 dihydroxyacetone pH 7.0, 25°C Mesocricetus auratus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.10 cytosol
-
 Cavia porcellus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.10 Cavia porcellus Q920N9
-
-
1.1.1.10 Homo sapiens Q7Z4W1
-
-
1.1.1.10 Mesocricetus auratus Q91XV4
-
-
1.1.1.10 Mus musculus Q91X52
-
-
1.1.1.10 Rattus norvegicus Q920P0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.10 recombinant enzyme from Escherichia coli, native from liver Cavia porcellus
1.1.1.10 recombinant enzyme from Escherichia coli, native from liver Mesocricetus auratus

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.1.10 xylitol + NADP+ = L-xylulose + NADPH + H+ enzyme with dual function showing L-xylulose reductase and dicarbonyl reductase activities Mus musculus
a
1.1.1.10 xylitol + NADP+ = L-xylulose + NADPH + H+ enzyme with dual function showing L-xylulose reductase and dicarbonyl reductase activities Rattus norvegicus
a
1.1.1.10 xylitol + NADP+ = L-xylulose + NADPH + H+ enzyme with dual function showing L-xylulose reductase and dicarbonyl reductase activities Cavia porcellus
a
1.1.1.10 xylitol + NADP+ = L-xylulose + NADPH + H+ enzyme with dual function showing L-xylulose reductase and dicarbonyl reductase activities Mesocricetus auratus
a
1.1.1.10 xylitol + NADP+ = L-xylulose + NADPH + H+ enzyme with dual function showing L-xylulose reductase and dicarbonyl reductase activities, it is probably identical with sperm 34 kDa protein P34H and diacetyl reductase, EC 1.1.1.5 Homo sapiens
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.10 brain low expression level Homo sapiens
-
1.1.1.10 brain low expression level Mus musculus
-
1.1.1.10 brain low expression level Rattus norvegicus
-
1.1.1.10 brain low expression level Cavia porcellus
-
1.1.1.10 brain low expression level Mesocricetus auratus
-
1.1.1.10 epididymis
-
 Homo sapiens
-
1.1.1.10 epididymis
-
 Cavia porcellus
-
1.1.1.10 epididymis high content Mus musculus
-
1.1.1.10 epididymis low expression level Rattus norvegicus
-
1.1.1.10 epididymis low expression level Mesocricetus auratus
-
1.1.1.10 heart
-
 Cavia porcellus
-
1.1.1.10 heart low expression level Homo sapiens
-
1.1.1.10 heart low expression level Mus musculus
-
1.1.1.10 heart low expression level Rattus norvegicus
-
1.1.1.10 heart low expression level Mesocricetus auratus
-
1.1.1.10 kidney high content Homo sapiens
-
1.1.1.10 kidney high content Mus musculus
-
1.1.1.10 kidney high content Rattus norvegicus
-
1.1.1.10 kidney high content Cavia porcellus
-
1.1.1.10 kidney high content Mesocricetus auratus
-
1.1.1.10 liver
-
 Mus musculus
-
1.1.1.10 liver high content Homo sapiens
-
1.1.1.10 liver high content Rattus norvegicus
-
1.1.1.10 liver high content Cavia porcellus
-
1.1.1.10 liver high content Mesocricetus auratus
-
1.1.1.10 lung
-
 Mus musculus
-
1.1.1.10 lung high content Cavia porcellus
-
1.1.1.10 lung low expression level Homo sapiens
-
1.1.1.10 lung low expression level Rattus norvegicus
-
1.1.1.10 lung low expression level Mesocricetus auratus
-
1.1.1.10 spleen
-
 Rattus norvegicus
-
1.1.1.10 spleen low expression level Homo sapiens
-
1.1.1.10 spleen low expression level Mus musculus
-
1.1.1.10 spleen low expression level Cavia porcellus
-
1.1.1.10 spleen low expression level Mesocricetus auratus
-
1.1.1.10 testis low expression level Homo sapiens
-
1.1.1.10 testis low expression level Mus musculus
-
1.1.1.10 testis low expression level Rattus norvegicus
-
1.1.1.10 testis low expression level Cavia porcellus
-
1.1.1.10 testis low expression level Mesocricetus auratus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.10 143
-
 purified native enzyme, L-xylulose reductase activity Cavia porcellus
1.1.1.10 642
-
 purified native enzyme, L-xylulose reductase activity Mesocricetus auratus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.10 1,4-dibromo-2,3-butanedione + NAD(P)H dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred Homo sapiens ? + NAD(P)+
-
 r
1.1.1.10 1,4-dibromo-2,3-butanedione + NAD(P)H dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred Mus musculus ? + NAD(P)+
-
 r
1.1.1.10 1,4-dibromo-2,3-butanedione + NAD(P)H dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred Rattus norvegicus ? + NAD(P)+
-
 r
1.1.1.10 1,4-dibromo-2,3-butanedione + NAD(P)H dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred Cavia porcellus ? + NAD(P)+
-
 r
1.1.1.10 1,4-dibromo-2,3-butanedione + NAD(P)H dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred Mesocricetus auratus ? + NAD(P)+
-
 r
1.1.1.10 D-erythrose + NADPH reductase activity Homo sapiens ?
-
 r
1.1.1.10 D-erythrose + NADPH reductase activity Mus musculus ?
-
 r
1.1.1.10 D-erythrose + NADPH reductase activity Rattus norvegicus ?
-
 r
1.1.1.10 D-erythrose + NADPH reductase activity Cavia porcellus ?
-
 r
1.1.1.10 D-erythrose + NADPH reductase activity Mesocricetus auratus ?
-
 r
1.1.1.10 D-ribulose + NADPH reductase activity Homo sapiens D-ribitol + NADP+
-
 r
1.1.1.10 D-ribulose + NADPH reductase activity Mus musculus D-ribitol + NADP+
-
 r
1.1.1.10 D-ribulose + NADPH reductase activity Rattus norvegicus D-ribitol + NADP+
-
 r
1.1.1.10 D-ribulose + NADPH reductase activity Cavia porcellus D-ribitol + NADP+
-
 r
1.1.1.10 D-ribulose + NADPH reductase activity Mesocricetus auratus D-ribitol + NADP+
-
 r
1.1.1.10 D-threose + NADPH reductase activity Homo sapiens D-threitol + NADP+
-
 r
1.1.1.10 D-threose + NADPH reductase activity Mus musculus D-threitol + NADP+
-
 r
1.1.1.10 D-threose + NADPH reductase activity Rattus norvegicus D-threitol + NADP+
-
 r
1.1.1.10 D-threose + NADPH reductase activity Cavia porcellus D-threitol + NADP+
-
 r
1.1.1.10 D-threose + NADPH reductase activity Mesocricetus auratus D-threitol + NADP+
-
 r
1.1.1.10 D-xylulose + NADH + H+
-
 Homo sapiens D-arabinitol + NAD+
-
 ?
1.1.1.10 D-xylulose + NADPH + H+ reductase activity Homo sapiens D-xylitol + NADP+
-
 r
1.1.1.10 D-xylulose + NADPH + H+ reductase activity Mus musculus D-xylitol + NADP+
-
 r
1.1.1.10 D-xylulose + NADPH + H+ reductase activity Rattus norvegicus D-xylitol + NADP+
-
 r
1.1.1.10 D-xylulose + NADPH + H+ reductase activity Cavia porcellus D-xylitol + NADP+
-
 r
1.1.1.10 D-xylulose + NADPH + H+ reductase activity Mesocricetus auratus D-xylitol + NADP+
-
 r
1.1.1.10 diacetyl + NAD(P)H
-
 Mus musculus acetoin + NAD(P)+
-
 ?
1.1.1.10 diacetyl + NAD(P)H
-
 Rattus norvegicus acetoin + NAD(P)+
-
 ?
1.1.1.10 diacetyl + NAD(P)H dicarbonyl reductase activity, NADPH is the preferred cofactor Homo sapiens acetoin + NAD(P)+
-
 r
1.1.1.10 diacetyl + NAD(P)H dicarbonyl reductase activity, NADPH is the preferred cofactor Mus musculus acetoin + NAD(P)+
-
 r
1.1.1.10 diacetyl + NAD(P)H dicarbonyl reductase activity, NADPH is the preferred cofactor Rattus norvegicus acetoin + NAD(P)+
-
 r
1.1.1.10 diacetyl + NAD(P)H dicarbonyl reductase activity, NADPH is the preferred cofactor Cavia porcellus acetoin + NAD(P)+
-
 r
1.1.1.10 diacetyl + NAD(P)H dicarbonyl reductase activity, NADPH is the preferred cofactor Mesocricetus auratus acetoin + NAD(P)+
-
 r
1.1.1.10 DL-glyceraldehyde + NADPH reductase activity, forward reaction is highly preferred Homo sapiens dihydroxyacetone + NADP+
-
 r
1.1.1.10 DL-glyceraldehyde + NADPH reductase activity, forward reaction is highly preferred Mus musculus dihydroxyacetone + NADP+
-
 r
1.1.1.10 DL-glyceraldehyde + NADPH reductase activity, forward reaction is highly preferred Rattus norvegicus dihydroxyacetone + NADP+
-
 r
1.1.1.10 DL-glyceraldehyde + NADPH reductase activity, forward reaction is highly preferred Cavia porcellus dihydroxyacetone + NADP+
-
 r
1.1.1.10 DL-glyceraldehyde + NADPH reductase activity, forward reaction is highly preferred Mesocricetus auratus dihydroxyacetone + NADP+
-
 r
1.1.1.10 DL-threitol + NAD+
-
 Homo sapiens D-threose + NADH
-
 ?
1.1.1.10 DL-threitol + NAD+
-
 Mus musculus D-threose + NADH
-
 ?
1.1.1.10 DL-threitol + NAD+
-
 Mesocricetus auratus D-threose + NADH
-
 ?
1.1.1.10 L-erythrulose + NADPH reductase activity Homo sapiens ?
-
 r
1.1.1.10 L-erythrulose + NADPH reductase activity Mus musculus ?
-
 r
1.1.1.10 L-erythrulose + NADPH reductase activity Rattus norvegicus ?
-
 r
1.1.1.10 L-erythrulose + NADPH reductase activity Cavia porcellus ?
-
 r
1.1.1.10 L-erythrulose + NADPH reductase activity Mesocricetus auratus ?
-
 r
1.1.1.10 L-threose + NADPH reductase activity Homo sapiens L-threitol + NADP+
-
 r
1.1.1.10 L-threose + NADPH reductase activity Mus musculus L-threitol + NADP+
-
 r
1.1.1.10 L-threose + NADPH reductase activity Rattus norvegicus L-threitol + NADP+
-
 r
1.1.1.10 L-threose + NADPH reductase activity Cavia porcellus L-threitol + NADP+
-
 r
1.1.1.10 L-threose + NADPH reductase activity Mesocricetus auratus L-threitol + NADP+
-
 r
1.1.1.10 L-xylulose + NADH + H+
-
 Homo sapiens xylitol + NAD+
-
 r
1.1.1.10 L-xylulose + NADH + H+
-
 Mus musculus xylitol + NAD+
-
 r
1.1.1.10 L-xylulose + NADH + H+
-
 Rattus norvegicus xylitol + NAD+
-
 r
1.1.1.10 L-xylulose + NADH + H+
-
 Cavia porcellus xylitol + NAD+
-
 r
1.1.1.10 L-xylulose + NADPH + H+
-
 Mus musculus L-xylitol + NADP+
-
 ?
1.1.1.10 L-xylulose + NADPH + H+ reductase activity Homo sapiens L-xylitol + NADP+
-
 r
1.1.1.10 L-xylulose + NADPH + H+ reductase activity Mus musculus L-xylitol + NADP+
-
 r
1.1.1.10 L-xylulose + NADPH + H+ reductase activity Rattus norvegicus L-xylitol + NADP+
-
 r
1.1.1.10 L-xylulose + NADPH + H+ reductase activity Cavia porcellus L-xylitol + NADP+
-
 r
1.1.1.10 L-xylulose + NADPH + H+ reductase activity Mesocricetus auratus L-xylitol + NADP+
-
 r
1.1.1.10 L-xylulose + NADPH + H+
-
 Mesocricetus auratus xylitol + NADP+
-
 r
1.1.1.10 additional information substrate specificity for dicarbonyl reductase activity, overview Homo sapiens ?
-
 ?
1.1.1.10 additional information substrate specificity for dicarbonyl reductase activity, overview Mus musculus ?
-
 ?
1.1.1.10 additional information substrate specificity for dicarbonyl reductase activity, overview Rattus norvegicus ?
-
 ?
1.1.1.10 additional information substrate specificity for dicarbonyl reductase activity, overview Cavia porcellus ?
-
 ?
1.1.1.10 additional information substrate specificity for dicarbonyl reductase activity, overview Mesocricetus auratus ?
-
 ?
1.1.1.10 xylitol + NAD+
-
 Homo sapiens L-xylulose + NADH + H+
-
 r
1.1.1.10 xylitol + NAD+
-
 Mus musculus L-xylulose + NADH + H+
-
 r
1.1.1.10 xylitol + NAD+
-
 Rattus norvegicus L-xylulose + NADH + H+
-
 r
1.1.1.10 xylitol + NAD+
-
 Mesocricetus auratus L-xylulose + NADH + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.1.10 P34H
-
 Homo sapiens
1.1.1.10 XR
-
 Homo sapiens
1.1.1.10 XR
-
 Mus musculus
1.1.1.10 XR
-
 Rattus norvegicus
1.1.1.10 XR
-
 Cavia porcellus
1.1.1.10 XR
-
 Mesocricetus auratus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.10 25
-
 assay at Homo sapiens
1.1.1.10 25
-
 assay at Mus musculus
1.1.1.10 25
-
 assay at Rattus norvegicus
1.1.1.10 25
-
 assay at Cavia porcellus
1.1.1.10 25
-
 assay at Mesocricetus auratus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.10 0.1
-
 D-xylulose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.23
-
 dihydroxyacetone pH 7.0, 25°C Homo sapiens
1.1.1.10 0.43
-
 D-erythrose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.48
-
 D-threitol pH 7.0, 25°C Homo sapiens
1.1.1.10 0.52
-
 DL-glyceraldehyde pH 7.0, 25°C Homo sapiens
1.1.1.10 0.52
-
 D-ribulose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.52
-
 L-threose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.6
-
 xylitol pH 7.0, 25°C Homo sapiens
1.1.1.10 0.6
-
 L-erythrulose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.65
-
 NADP+ pH 7.0, 25°C Homo sapiens
1.1.1.10 0.65
-
 L-xylulose pH 7.0, 25°C Homo sapiens
1.1.1.10 0.65
-
 acetoin pH 7.0, 25°C Homo sapiens
1.1.1.10 0.82
-
 D-threose pH 7.0, 25°C Homo sapiens
1.1.1.10 1.5
-
 NADPH pH 7.0, 25°C Homo sapiens
1.1.1.10 1.5
-
 NAD+ pH 7.0, 25°C Homo sapiens
1.1.1.10 1.6
-
 diacetyl pH 7.0, 25°C Homo sapiens
1.1.1.10 2 8 NADH pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 2 8 xylitol pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 2 8 D-erythrose pH 7.0, 25°C Cavia porcellus
1.1.1.10 2 8 D-threose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 3 6 L-xylulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 3
-
 acetoin pH 7.0, 25°C Mus musculus
1.1.1.10 3.3
-
 dihydroxyacetone pH 7.0, 25°C Mus musculus
1.1.1.10 3.8
-
 NADH pH 7.0, 25°C Homo sapiens
1.1.1.10 3.8
-
 dihydroxyacetone pH 7.0, 25°C Cavia porcellus
1.1.1.10 5.1
-
 dihydroxyacetone pH 7.0, 25°C Rattus norvegicus
1.1.1.10 6.9
-
 D-xylulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 6.9
-
 acetoin pH 7.0, 25°C Rattus norvegicus
1.1.1.10 6.9
-
 acetoin pH 7.0, 25°C Cavia porcellus
1.1.1.10 6.9
-
 acetoin pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 7.4
-
 D-xylulose pH 7.0, 25°C Mus musculus
1.1.1.10 7.8
-
 D-ribulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 8.7
-
 dihydroxyacetone pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 10
-
 NADP+ pH 7.0, 25°C Rattus norvegicus
1.1.1.10 10
-
 xylitol pH 7.0, 25°C Rattus norvegicus
1.1.1.10 12
-
 D-threitol pH 7.0, 25°C Rattus norvegicus
1.1.1.10 15
-
 NADP+ pH 7.0, 25°C Mus musculus
1.1.1.10 15
-
 D-threitol pH 7.0, 25°C Cavia porcellus
1.1.1.10 16
-
 L-threose pH 7.0, 25°C Mus musculus
1.1.1.10 16
-
 L-threose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 16
-
 D-threitol pH 7.0, 25°C Mus musculus
1.1.1.10 16
-
 D-threitol pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 17
-
 xylitol pH 7.0, 25°C Mus musculus
1.1.1.10 18
-
 D-xylulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 18
-
 D-erythrose pH 7.0, 25°C Mus musculus
1.1.1.10 18
-
 D-erythrose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 19
-
 D-xylulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 19
-
 D-ribulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 20
-
 xylitol pH 7.0, 25°C Cavia porcellus
1.1.1.10 20
-
 DL-glyceraldehyde pH 7.0, 25°C Cavia porcellus
1.1.1.10 21
-
 DL-glyceraldehyde pH 7.0, 25°C Rattus norvegicus
1.1.1.10 22
-
 DL-glyceraldehyde pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 23
-
 NADH pH 7.0, 25°C Rattus norvegicus
1.1.1.10 23
-
 NADP+ pH 7.0, 25°C Cavia porcellus
1.1.1.10 23
-
 D-erythrose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 23
-
 L-erythrulose pH 7.0, 25°C Mus musculus
1.1.1.10 23
-
 D-threose pH 7.0, 25°C Mus musculus
1.1.1.10 23
-
 L-threose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 24
-
 DL-glyceraldehyde pH 7.0, 25°C Mus musculus
1.1.1.10 24
-
 diacetyl pH 7.0, 25°C Cavia porcellus
1.1.1.10 24
-
 L-erythrulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 25
-
 NADPH pH 7.0, 25°C Rattus norvegicus
1.1.1.10 25
-
 diacetyl pH 7.0, 25°C Rattus norvegicus
1.1.1.10 25
-
 L-erythrulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 25
-
 L-erythrulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 26
-
 NADPH pH 7.0, 25°C Cavia porcellus
1.1.1.10 26
-
 NADP+ pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 26
-
 D-ribulose pH 7.0, 25°C Mus musculus
1.1.1.10 27
-
 NADPH pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 27
-
 L-threose pH 7.0, 25°C Cavia porcellus
1.1.1.10 30
-
 diacetyl pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 31
-
 D-ribulose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 31
-
 D-threose pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 32
-
 D-threose pH 7.0, 25°C Cavia porcellus
1.1.1.10 34
-
 NADPH pH 7.0, 25°C Mus musculus
1.1.1.10 37
-
 L-xylulose pH 7.0, 25°C Mus musculus
1.1.1.10 37
-
 L-xylulose pH 7.0, 25°C Cavia porcellus
1.1.1.10 39
-
 L-xylulose pH 7.0, 25°C Rattus norvegicus
1.1.1.10 41
-
 NAD+ pH 7.0, 25°C Rattus norvegicus
1.1.1.10 41
-
 NADH pH 7.0, 25°C Mus musculus
1.1.1.10 41
-
 diacetyl pH 7.0, 25°C Mus musculus
1.1.1.10 44
-
 NAD+ pH 7.0, 25°C Mesocricetus auratus
1.1.1.10 55
-
 NAD+ pH 7.0, 25°C Mus musculus
1.1.1.10 76
-
 NADH pH 7.0, 25°C Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.10 7
-
 assay at Homo sapiens
1.1.1.10 7
-
 assay at Mus musculus
1.1.1.10 7
-
 assay at Rattus norvegicus
1.1.1.10 7
-
 assay at Cavia porcellus
1.1.1.10 7
-
 assay at Mesocricetus auratus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.10 NAD+
-
 Homo sapiens
1.1.1.10 NAD+
-
 Mus musculus
1.1.1.10 NAD+
-
 Rattus norvegicus
1.1.1.10 NAD+
-
 Cavia porcellus
1.1.1.10 NAD+
-
 Mesocricetus auratus
1.1.1.10 NADH
-
 Homo sapiens
1.1.1.10 NADH
-
 Mus musculus
1.1.1.10 NADH
-
 Rattus norvegicus
1.1.1.10 NADH
-
 Cavia porcellus
1.1.1.10 NADH
-
 Mesocricetus auratus
1.1.1.10 NADP+ preferred cofactor, reverse reaction Homo sapiens
1.1.1.10 NADP+ preferred cofactor, reverse reaction Mus musculus
1.1.1.10 NADP+ preferred cofactor, reverse reaction Rattus norvegicus
1.1.1.10 NADP+ preferred cofactor, reverse reaction Cavia porcellus
1.1.1.10 NADP+ preferred cofactor, reverse reaction Mesocricetus auratus
1.1.1.10 NADPH preferred cofactor, forward reaction Homo sapiens
1.1.1.10 NADPH preferred cofactor, forward reaction Mus musculus
1.1.1.10 NADPH preferred cofactor, forward reaction Rattus norvegicus
1.1.1.10 NADPH preferred cofactor, forward reaction Cavia porcellus
1.1.1.10 NADPH preferred cofactor, forward reaction Mesocricetus auratus