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Literature summary extracted from

  • Krakowiak, P.A.; Wassif, C.A.; Kratz, L.; Cozma, D.; Kovarova, M.; Harris, G.; Grinberg, A.; Yang, Y.; Hunter, A.G.; Tsokos, M.; Kelley, R.I.; Porter, F.D.
    Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency (2003), Hum. Mol. Genet., 12, 1631-1641.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.20 lathosterol + O2 + ferrocytochrome b5 Mus musculus
-
7-dehydrocholesterol + H2O + ferricytochrome b5
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.20 Mus musculus
-
Sc5d deletion leads to intrauterine growth tardation, craniofacial abnormalities, including cleft palate and micrognathia, and limb patterning defects
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.20 lathosterol + O2 + ferrocytochrome b5
-
Mus musculus 7-dehydrocholesterol + H2O + ferricytochrome b5
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.20 Sc5d
-
Mus musculus