BRENDA - Enzyme Database

Proteus mirabilis dehydrogenates aldonates and aldarates with an (R)-configured alpha-carbon atom to the corresponding 2-oxocarboxylates

Schinschel, C.; Simon, H.; Bioorg. Med. Chem. 2, 483-491 (1994)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.1.99.30
0.025
-
carboxamido-methyl viologen
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.042
-
benzyl viologen
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.19
-
oxidized antraquinone-2,6-disulfonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.3
-
D-ribonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.42
-
galactarate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.48
-
D-galactonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.64
-
6-phospho-D-gluconate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.64
-
D-gulonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.66
-
Lactobionate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.68
-
D-lactate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.92
-
L-mannonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.98
-
D-gluconate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
1.27
-
D-xylonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
1.46
-
L-arabinuronate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
1.68
-
D-glucarate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
2.03
-
L-arabinoic acid
pH 8.5, 38°C
Proteus mirabilis
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.99.30
Proteus mirabilis
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
1.1.99.30
a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor
aldonates and aldarates with an (R)-configured alpha-carbon atom are converted to the corresponding 2-oxocarboxylates
Proteus mirabilis
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.99.30
6-phospho-D-gluconate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
6-phospho-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
6-phospho-D-gluconate + oxidized benzyl viologen
-
654958
Proteus mirabilis
6-phospho-D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
6-phospho-D-gluconate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
6-phospho-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-galactonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-lyxo-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-galactonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-lyxo-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-galactonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-lyxo-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-glucarate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
2-oxo-D-glucarate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-glucarate + oxidized benzyl viologen
-
654958
Proteus mirabilis
2-oxo-D-glucarate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-glucarate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
2-oxo-D-glucarate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-gluconate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-gluconate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-gluconate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-gulonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-gulonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-gulonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-lactate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
pyruvate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-lactate + oxidized benzyl viologen
-
654958
Proteus mirabilis
pyruvate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-lactate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
pyruvate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-ribonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-ribonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-erythro-pent-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-ribonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-xylonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-threo-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-xylonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-threo-pent-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-xylonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-threo-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
galactarate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
2-oxogalactarate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
galactarate + oxidized benzyl viologen
-
654958
Proteus mirabilis
2-oxogalactarate + reduced benzyl viologen
-
-
-
r
1.1.99.30
galactarate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
2-oxogalactarate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
L-arabinonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
L-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
L-arabinonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
L-erythro-pent-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
L-arabinonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
L-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
L-arabinuronate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
? + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
L-arabinuronate + oxidized benzyl viologen
-
654958
Proteus mirabilis
? + reduced benzyl viologen
-
-
-
r
1.1.99.30
L-arabinuronate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
? + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
L-mannonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
L-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
L-mannonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
L-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
L-mannonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
L-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
lactobionate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
lactobionate + oxidized benzyl viologen
-
654958
Proteus mirabilis
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
lactobionate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
additional information
product determination, stereochemistry and molecule conformations, products appear in pyranose, furanose or lactone form, overview
654958
Proteus mirabilis
?
-
-
-
-
1.1.99.30
phenylpyruvate + reduced carbamoylmethyl viologen
-
654958
Proteus mirabilis
(2R)-phenyllactate + oxidized carbamoylmethyl viologen
-
-
-
-
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
1.1.99.30
25
-
assay at
Proteus mirabilis
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
1.1.99.30
8.5
-
assay at
Proteus mirabilis
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.1.99.30
0.025
-
carboxamido-methyl viologen
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.042
-
benzyl viologen
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.19
-
oxidized antraquinone-2,6-disulfonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.3
-
D-ribonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.42
-
galactarate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.48
-
D-galactonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.64
-
6-phospho-D-gluconate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.64
-
D-gulonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.66
-
Lactobionate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.68
-
D-lactate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.92
-
L-mannonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
0.98
-
D-gluconate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
1.27
-
D-xylonate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
1.46
-
L-arabinuronate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
1.68
-
D-glucarate
pH 8.5, 38°C
Proteus mirabilis
1.1.99.30
2.03
-
L-arabinoic acid
pH 8.5, 38°C
Proteus mirabilis
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.99.30
6-phospho-D-gluconate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
6-phospho-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
6-phospho-D-gluconate + oxidized benzyl viologen
-
654958
Proteus mirabilis
6-phospho-D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
6-phospho-D-gluconate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
6-phospho-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-galactonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-lyxo-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-galactonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-lyxo-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-galactonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-lyxo-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-glucarate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
2-oxo-D-glucarate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-glucarate + oxidized benzyl viologen
-
654958
Proteus mirabilis
2-oxo-D-glucarate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-glucarate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
2-oxo-D-glucarate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-gluconate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-gluconate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-gluconate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-gulonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-gulonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-gulonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-lactate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
pyruvate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-lactate + oxidized benzyl viologen
-
654958
Proteus mirabilis
pyruvate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-lactate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
pyruvate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-ribonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-ribonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-erythro-pent-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-ribonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
D-xylonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
D-threo-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
D-xylonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
D-threo-pent-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
D-xylonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
D-threo-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
galactarate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
2-oxogalactarate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
galactarate + oxidized benzyl viologen
-
654958
Proteus mirabilis
2-oxogalactarate + reduced benzyl viologen
-
-
-
r
1.1.99.30
galactarate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
2-oxogalactarate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
L-arabinonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
L-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
L-arabinonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
L-erythro-pent-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
L-arabinonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
L-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
L-arabinuronate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
? + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
L-arabinuronate + oxidized benzyl viologen
-
654958
Proteus mirabilis
? + reduced benzyl viologen
-
-
-
r
1.1.99.30
L-arabinuronate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
? + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
L-mannonate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
L-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
L-mannonate + oxidized benzyl viologen
-
654958
Proteus mirabilis
L-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
L-mannonate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
L-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
lactobionate + oxidized anthraquinone-2,6-disulfonate
-
654958
Proteus mirabilis
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
-
-
r
1.1.99.30
lactobionate + oxidized benzyl viologen
-
654958
Proteus mirabilis
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
-
-
r
1.1.99.30
lactobionate + oxidized carboxamido-methyl viologen
-
654958
Proteus mirabilis
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
-
-
r
1.1.99.30
additional information
product determination, stereochemistry and molecule conformations, products appear in pyranose, furanose or lactone form, overview
654958
Proteus mirabilis
?
-
-
-
-
1.1.99.30
phenylpyruvate + reduced carbamoylmethyl viologen
-
654958
Proteus mirabilis
(2R)-phenyllactate + oxidized carbamoylmethyl viologen
-
-
-
-
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
1.1.99.30
25
-
assay at
Proteus mirabilis
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
1.1.99.30
8.5
-
assay at
Proteus mirabilis