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Literature summary extracted from

  • Gadda, G.
    Kinetic mechanism of choline oxidase from Arthrobacter globiformis (2003), Biochim. Biophys. Acta, 1646, 112-118.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.3.17 0.55
-
choline 19°C, pH 7.0 Arthrobacter globiformis
1.1.3.17 2.35
-
betaine-aldehyde 19°C, pH 7.0 Arthrobacter globiformis

Organism

EC Number Organism UniProt Comment Textmining
1.1.3.17 Arthrobacter globiformis
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.3.17 choline + O2 = betaine aldehyde + H2O2 sequential mechanism with oxygen reacting with the reduced enzyme before release of the betaine-aldede or glycine-betaine, kinetic step in the oxidation of choline to the ladehyde is partially rate-limiting Arthrobacter globiformis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.3.17 betaine aldehyde + O2 + H2O
-
Arthrobacter globiformis betaine + H2O2
-
?
1.1.3.17 choline + O2
-
Arthrobacter globiformis betaine aldehyde + H2O2
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.3.17 1.71
-
betaine-aldehyde 19°C, pH 7.0 Arthrobacter globiformis
1.1.3.17 2.24
-
choline 19°C, pH 7.0 Arthrobacter globiformis