EC Number | Cloned (Comment) | Organism |
---|---|---|
1.4.1.21 | - |
Thermotoga maritima |
EC Number | General Stability | Organism |
---|---|---|
1.4.1.21 | stable | Thermotoga maritima |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.4.1.21 | L-malate | competitive | Thermotoga maritima | |
1.4.1.21 | NH4+ | competitive | Thermotoga maritima |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.1.21 | 0.067 | - |
L-Asp | cofactor NAD+ | Thermotoga maritima | |
1.4.1.21 | 0.067 | - |
L-aspartate | +/- 0.008, with NAD+ | Thermotoga maritima | |
1.4.1.21 | 0.25 | - |
NAD+ | - |
Thermotoga maritima | |
1.4.1.21 | 0.25 | - |
NAD+ | +/- 0.02 | Thermotoga maritima | |
1.4.1.21 | 0.72 | - |
NADP+ | - |
Thermotoga maritima | |
1.4.1.21 | 0.72 | - |
NADP+ | +/- 0.04 | Thermotoga maritima | |
1.4.1.21 | 1.2 | - |
L-Asp | cofactor: NADP+ | Thermotoga maritima | |
1.4.1.21 | 1.2 | - |
L-aspartate | +/- 0.05, with NADP+ | Thermotoga maritima |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.1.21 | L-aspartate + NAD(P)+ | Thermotoga maritima | - |
oxaloacetate + NH4+ + NAD(P)H | - |
? | |
1.4.1.21 | oxaloacetate + NAD(P)H + NH4+ | Thermotoga maritima | - |
L-aspartate + NAD(P)+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.1.21 | Thermotoga maritima | Q9X1X6 | - |
- |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.4.1.21 | 1.63 | - |
+/- 0.15, L-aspartate with NAD+ | Thermotoga maritima |
1.4.1.21 | 3.36 | - |
+/- 0.25, NAD+ with L-aspartate | Thermotoga maritima |
1.4.1.21 | 9.51 | - |
+/- 0.17, L-aspartate with NADP+ | Thermotoga maritima |
1.4.1.21 | 12.32 | - |
+/- 0.88, NADP+ with L-aspartate | Thermotoga maritima |
EC Number | Storage Stability | Organism |
---|---|---|
1.4.1.21 | 4°C, 5% glycerol, 0.5 M NaCl, pH 7.5, no loss in activity after several months | Thermotoga maritima |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.1.21 | L-aspartate + H2O + NAD+ | - |
Thermotoga maritima | oxaloacetate + NH3 + NADH + H+ | - |
r | |
1.4.1.21 | L-aspartate + NAD(P)+ | - |
Thermotoga maritima | oxaloacetate + NH4+ + NAD(P)H | - |
? | |
1.4.1.21 | L-aspartate + NAD(P)+ | - |
Thermotoga maritima | oxaloacetate + NH4+ + NAD(P)H | - |
r | |
1.4.1.21 | oxaloacetate + NAD(P)H + NH4+ | - |
Thermotoga maritima | L-aspartate + NAD(P)+ | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.4.1.21 | dimer | crystal structure | Thermotoga maritima |
1.4.1.21 | dimer | from crystal structure | Thermotoga maritima |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.4.1.21 | L-aspartate dehydrogenase | - |
Thermotoga maritima |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.4.1.21 | 70 | - |
- |
Thermotoga maritima |
EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.4.1.21 | 25 | 90 | - |
Thermotoga maritima |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.1.21 | 0.78 | - |
L-Asp | cofactor NAD+ | Thermotoga maritima | |
1.4.1.21 | 0.78 | - |
L-aspartate | +/- 0.02, with NAD+ | Thermotoga maritima | |
1.4.1.21 | 1.2 | - |
NAD+ | - |
Thermotoga maritima | |
1.4.1.21 | 1.2 | - |
NAD+ | +/- 0.04, with L-aspartate | Thermotoga maritima | |
1.4.1.21 | 4.9 | - |
L-Asp | cofactor NADP+ | Thermotoga maritima | |
1.4.1.21 | 4.9 | - |
L-aspartate | +/- 0.09, with NADP+ | Thermotoga maritima | |
1.4.1.21 | 7.2 | - |
NADP+ | - |
Thermotoga maritima | |
1.4.1.21 | 7.2 | - |
NADP+ | +/- 0.17, with L-aspartate | Thermotoga maritima |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.4.1.21 | 8 | - |
oxaloacetate animation | Thermotoga maritima |
1.4.1.21 | 8 | - |
oxaloacetate amination | Thermotoga maritima |
1.4.1.21 | 9.8 | - |
L-Asp oxidation | Thermotoga maritima |
1.4.1.21 | 9.8 | - |
L-aspartate oxidation | Thermotoga maritima |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
1.4.1.21 | 8 | 10.5 | L-Asp oxidation | Thermotoga maritima |
1.4.1.21 | 8 | 10.5 | L-aspartate oxidation | Thermotoga maritima |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.4.1.21 | NAD+ | - |
Thermotoga maritima | |
1.4.1.21 | NADH | - |
Thermotoga maritima | |
1.4.1.21 | NADP+ | - |
Thermotoga maritima | |
1.4.1.21 | NADPH | - |
Thermotoga maritima |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.1.21 | 4.02 | - |
L-malate | +/- 0.48 | Thermotoga maritima | |
1.4.1.21 | 32.5 | - |
NH4+ | +/- 4.9 | Thermotoga maritima |