EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.17 | 4-nitrobenzoate | inhibition of propanoyl-CoA formation in solubilized mitochondria | Rattus norvegicus | |
6.2.1.17 | Butyrate | inhibition of propanoyl-CoA formation in solubilized mitochondria | Rattus norvegicus | |
6.2.1.17 | Octanoate | inhibition of propanoyl-CoA formation in solubilized mitochondria | Rattus norvegicus | |
6.2.1.17 | salicylate | inhibition of propanoyl-CoA formation in solubilized mitochondria | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.2.1.17 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.17 | ATP + propanoate + CoA | Rattus norvegicus | intracellular accumulation of propanoyl-CoA is associated with impairment of important heptic metabolic pathways. Since propanoate absorbed from the intestine can be converted to propanoyl-CoA in the liver, inhibition of propanoyl-CoA synthesis from propanoate and CoA may provide a strategy for decreasing toxicity from plasma propanoate | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.2.1.17 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.2.1.17 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.17 | ATP + propanoate + CoA | - |
Rattus norvegicus | AMP + diphosphate + propanoyl-CoA | - |
? | |
6.2.1.17 | ATP + propanoate + CoA | intracellular accumulation of propanoyl-CoA is associated with impairment of important heptic metabolic pathways. Since propanoate absorbed from the intestine can be converted to propanoyl-CoA in the liver, inhibition of propanoyl-CoA synthesis from propanoate and CoA may provide a strategy for decreasing toxicity from plasma propanoate | Rattus norvegicus | ? | - |
? |