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Literature summary extracted from
- Effect of acidic phospholipids on the structural properties of recombinant cytosolic human glyoxalase II (2002), Proteins, 48, 126-133.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.2.6 | acidic phospholipids | noncompetitive inhibition, lower thermal stability of the enzyme, inhibit protein intermolecular interactions/aggregation by thermal denaturation, small changes in the secondary structure are caused | Homo sapiens | |
| 3.1.2.6 | anionic phospholipids | noncompetitive inhibition, cytosolic isozyme | Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.2.6 | cytosol | cytosolic isozyme, soluble | Homo sapiens | 5829 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.2.6 | Homo sapiens | - |
purified recombinant cytosolic isozyme | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.2.6 | liver | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.6 | S-D-lactoylglutathione + H2O | - |
Homo sapiens | glutathione + D-lactate | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.2.6 | acetoacetylglutathione hydrolase | - |
Homo sapiens |
| 3.1.2.6 | Germ cell specific protein | - |
Homo sapiens |
| 3.1.2.6 | GII | - |
Homo sapiens |
| 3.1.2.6 | GLO II | - |
Homo sapiens |
| 3.1.2.6 | glyoxalase II | - |
Homo sapiens |
| 3.1.2.6 | hydrolase, acetoacetylglutathione | - |
Homo sapiens |
| 3.1.2.6 | hydrolase, hydroxyacylglutathione | - |
Homo sapiens |
| 3.1.2.6 | Round spermatid protein RSP29 | - |
Homo sapiens |
| 3.1.2.6 | S-2-hydroxylacylglutathione hydrolase | - |
Homo sapiens |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.6 | 25 | - |
assay at | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.6 | 7.2 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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