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Literature summary extracted from

  • Ruano, M.J.; Sanchez-Martin, M.M.; Alonso, J.M.; Hueso, P.
    Changes of acetylcholinesterase activity in brain areas and liver of sucrose- and ethanol-fed rats (2000), Neurochem. Res., 25, 461-470.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.7 n-butanol inhibits below 100 mM and activates above 100 mM Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 n-butanol inhibits below 100 mM and activates above 100 mM Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.7 membrane
-
 Rattus norvegicus 16020
-
3.1.1.7 soluble
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Rattus norvegicus
-
 male Wistar
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 brain
-
 Rattus norvegicus
-
3.1.1.7 cerebellum
-
 Rattus norvegicus
-
3.1.1.7 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylthiocholine + H2O
-
 Rattus norvegicus thiocholine + acetate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.7 50 60
-
 Rattus norvegicus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.1.7 10 50 membrane-bound enzyme from ethanol- and sucrose-treated rats is more stable at temperatures between 10°C and 50°C than the enzyme from untreated rats Rattus norvegicus
3.1.1.7 50
-
 enzyme retains 30-50% activity for 60 min Rattus norvegicus