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Literature summary extracted from

  • Li, W.; Srinivasula, S.M.; Chai, J.; Li, P.; Wu, J.W.; Zhang, Z.; Alnemri, E.S.; Shi, Y.
    Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi (2002), Nat. Struct. Biol., 9, 436-441.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.21.108 hanging drop vapor diffusion method Mammalia

Protein Variants

EC Number Protein Variants Comment Organism
3.4.21.108 F149D comparable level of binding to XIAP as the wild type-enzyme Mammalia
3.4.21.108 S306A comparable level of binding to XIAP as the wild type-enzyme Mammalia

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.108 36000
-
 3 * 36000, gel filtration Mammalia
3.4.21.108 110000
-
 gel filtration Mammalia

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.108 additional information Mammalia role in apoptosis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.108 Mammalia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.108 beta-casein + H2O
-
 Mammalia ?
-
 ?
3.4.21.108 additional information role in apoptosis Mammalia ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.108 trimer 3 * 36000, gel filtration Mammalia

Synonyms

EC Number Synonyms Comment Organism
3.4.21.108 HtrA2/Omi
-
 Mammalia