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Literature summary extracted from

  • Yoshida, Y.; Nakano, Y.; Amano, A.; Yoshimura, M.; Fukamachi, H.; Oho, T.; Koga, T.
    lcd from Streptococcus anginosus encodes a C-S lyase with alpha,beta-elimination activity that degrades L-cysteine (2002), Microbiology, 148, 3961-3970.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.1
-
 Streptococcus anginosus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.1 0.62
-
 L-cysteine pH 8.0, 37°C Streptococcus anginosus
4.4.1.1 1.29
-
 L-cystine pH 8.0, 37°C Streptococcus anginosus
4.4.1.1 2.75
-
 S-(2-aminoethyl)-L-cysteine pH 8.0, 37°C Streptococcus anginosus
4.4.1.1 3.27
-
 DL-cystathionine pH 8.0, 37°C Streptococcus anginosus
4.4.1.1 13.13
-
 S-methyl-L-cysteine pH 8.0, 37°C Streptococcus anginosus
4.4.1.1 28.41
-
 3-chloro-DL-alanine pH 8.0, 37°C Streptococcus anginosus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus anginosus

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Streptococcus anginosus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.4.1.1
-
 Streptococcus anginosus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 3-chloro-DL-alanine + H2O
-
 Streptococcus anginosus NH3 + ?
-
 ?
4.4.1.1 DL-cystathionine + H2O
-
 Streptococcus anginosus L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus anginosus sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cystine + 2 H2O
-
 Streptococcus anginosus 2 NH3 + 2 pyruvate + 2 hydrogen sulfide
-
 ?
4.4.1.1 L-methionine + H2O
-
 Streptococcus anginosus NH3 + ?
-
 ?
4.4.1.1 S-(2-aminoethyl)-L-cysteine + H2O
-
 Streptococcus anginosus NH3 + pyruvate + cysteamine
-
 ?
4.4.1.1 S-methyl-L-cysteine + H2O
-
 Streptococcus anginosus NH3 + pyruvate + methyl mercaptan
-
 ?

Subunits

EC Number Subunits Comment Organism
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus anginosus