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Literature summary extracted from

  • Ramadurai, L.; Lockwood, K.J.; Nadakavukaren, M.J.; Jayaswal, R.K.
    Characterization of a chromosomally encoded glycylglycine endopeptidase of Staphylococcus aureus (1999), Microbiology, 145, 801-808.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.75 overexpression in Escherichia coli Staphylococcus aureus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.75 ampicillin
-
 Staphylococcus aureus
3.4.24.75 Ba2+
-
 Staphylococcus aureus
3.4.24.75 Cu2+
-
 Staphylococcus aureus
3.4.24.75 diammonium sulfate
-
 Staphylococcus aureus
3.4.24.75 diethyldicarbonate
-
 Staphylococcus aureus
3.4.24.75 DTT
-
 Staphylococcus aureus
3.4.24.75 EDTA
-
 Staphylococcus aureus
3.4.24.75 Fe2+
-
 Staphylococcus aureus
3.4.24.75 HgCl2
-
 Staphylococcus aureus
3.4.24.75 KCl 100 mM Staphylococcus aureus
3.4.24.75 Mg2+
-
 Staphylococcus aureus
3.4.24.75 Mn2+
-
 Staphylococcus aureus
3.4.24.75 NaCl 100 mM Staphylococcus aureus
3.4.24.75 PMSF
-
 Staphylococcus aureus
3.4.24.75 Zn2+
-
 Staphylococcus aureus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.75 Zinc 0.9 mol zinc per mol LytM Staphylococcus aureus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.75 additional information Staphylococcus aureus LytM is expressed during early exponential phase and is overexpressed in an autolysis-defective mutant compared with the parent strain. LytM plays a role in cell growth ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.75 Staphylococcus aureus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.75
-
 Staphylococcus aureus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.75 additional information
-
-
 Staphylococcus aureus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.75 additional information LytM is expressed during early exponential phase and is overexpressed in an autolysis-defective mutant compared with the parent strain. LytM plays a role in cell growth Staphylococcus aureus ?
-
 ?
3.4.24.75 Peptidoglycan + H2O
-
 Staphylococcus aureus Fragments of peptidoglycan
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.24.75 100
-
 15 min, stable. Activity is destroyed after 30 min Staphylococcus aureus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.75 5 8
-
 Staphylococcus aureus