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Literature summary extracted from

  • Gruber, K.; Kratky, C.
    Biopolymers for biocatalysis: Structure and catalytic mechanism of hydroxynitrile lyases (2004), J. Polym. Sci. A, 42, 479-486.
No PubMed abstract available

Application

EC Number Application Comment Organism
4.1.2.11 synthesis first (S)-HNL used in organic solvents for the preparation of (S)-cyanohydrins Sorghum bicolor

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.11
-
 Sorghum bicolor

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.1.2.11
-
 Sorghum bicolor

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.2.11 benzoic acid
-
 Sorghum bicolor

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.11 cyanide + 4-hydroxybenzaldehyde Sorghum bicolor
-
 (S)-p-hydroxymandelonitrile
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.11 Sorghum bicolor P52708
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.11 cyanide + 4-hydroxybenzaldehyde
-
 Sorghum bicolor (S)-p-hydroxymandelonitrile
-
 ?
4.1.2.11 HCN + 4-hydroxybenzaldehyde (S)-specific Sorghum bicolor (S)-4-hydroxymandelonitrile
-
 ?
4.1.2.11 additional information substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates Sorghum bicolor ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.2.11 heterotetramer alpha2,beta2 heterotetramer consisting of two alpha,beta heterodimers Sorghum bicolor

Synonyms

EC Number Synonyms Comment Organism
4.1.2.11 HNL
-
 Sorghum bicolor
4.1.2.11 Hydroxynitrile lyase
-
 Sorghum bicolor
4.1.2.11 SbHNL
-
 Sorghum bicolor