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Literature summary extracted from

  • Acartuerk, F.; Parlatan, Z.I.; Saracoglu, O.F.
    Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans (2001), J. Pharm. Pharmacol., 53, 1499-1504.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 bestatin 92.5% inhibition at 0.005 mM Cavia porcellus
3.4.11.2 bestatin 73% inhibition at 0.005 mM Homo sapiens
3.4.11.2 bestatin 72.2% inhibition at 0.005 mM Oryctolagus cuniculus
3.4.11.2 bestatin 84% inhibition at 0.005 mM Ovis aries
3.4.11.2 bestatin 52% inhibition at 0.005 mM Rattus norvegicus
3.4.11.2 puromycin 34.1% inhibition at 0.05 mM Cavia porcellus
3.4.11.2 puromycin 78.1% inhibition at 0.05 mM Homo sapiens
3.4.11.2 puromycin 39.5% inhibition at 0.05 mM Oryctolagus cuniculus
3.4.11.2 puromycin 74.3% inhibition at 0.05 mM Ovis aries
3.4.11.2 puromycin 41.5% inhibition at 0.05 mM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Cavia porcellus
-
-
-
3.4.11.2 Homo sapiens
-
-
-
3.4.11.2 Oryctolagus cuniculus
-
-
-
3.4.11.2 Ovis aries
-
-
-
3.4.11.2 Rattus norvegicus
-
 femal Wistar rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 vagina
-
 Cavia porcellus
-
3.4.11.2 vagina
-
 Homo sapiens
-
3.4.11.2 vagina
-
 Rattus norvegicus
-
3.4.11.2 vagina
-
 Oryctolagus cuniculus
-
3.4.11.2 vagina
-
 Ovis aries
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.2 1.03
-
 cell extract Rattus norvegicus
3.4.11.2 1.38
-
 cell extract Homo sapiens
3.4.11.2 1.67
-
 cell extract Oryctolagus cuniculus
3.4.11.2 9.65
-
 cell extract Cavia porcellus
3.4.11.2 13.1
-
 cell extract Ovis aries

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-alaninyl 4-methoxy-2-naphthylamide + H2O
-
 Cavia porcellus L-alanine + 4-methoxy-2-naphthylamine
-
 ?
3.4.11.2 L-alaninyl 4-methoxy-2-naphthylamide + H2O
-
 Homo sapiens L-alanine + 4-methoxy-2-naphthylamine
-
 ?
3.4.11.2 L-alaninyl 4-methoxy-2-naphthylamide + H2O
-
 Rattus norvegicus L-alanine + 4-methoxy-2-naphthylamine
-
 ?
3.4.11.2 L-alaninyl 4-methoxy-2-naphthylamide + H2O
-
 Oryctolagus cuniculus L-alanine + 4-methoxy-2-naphthylamine
-
 ?
3.4.11.2 L-alaninyl 4-methoxy-2-naphthylamide + H2O
-
 Ovis aries L-alanine + 4-methoxy-2-naphthylamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 aminopeptidase N
-
 Cavia porcellus
3.4.11.2 aminopeptidase N
-
 Homo sapiens
3.4.11.2 aminopeptidase N
-
 Rattus norvegicus
3.4.11.2 aminopeptidase N
-
 Oryctolagus cuniculus
3.4.11.2 aminopeptidase N
-
 Ovis aries

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.11.2 37
-
 assay at Cavia porcellus
3.4.11.2 37
-
 assay at Homo sapiens
3.4.11.2 37
-
 assay at Rattus norvegicus
3.4.11.2 37
-
 assay at Oryctolagus cuniculus
3.4.11.2 37
-
 assay at Ovis aries

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.2 7.4
-
 assay at Cavia porcellus
3.4.11.2 7.4
-
 assay at Homo sapiens
3.4.11.2 7.4
-
 assay at Rattus norvegicus
3.4.11.2 7.4
-
 assay at Oryctolagus cuniculus
3.4.11.2 7.4
-
 assay at Ovis aries