Literature summary extracted from
Malashkevich, V.N.; Strop, P.; Keller, J.W.; Jansonius, J.N.; Toney, M.D.
Crystal structures of dialkylglycine decarboxylase inhibitor complexes (1999), J. Mol. Biol., 294, 193-200.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
4.1.1.64 |
in complex with four inhibitors |
Burkholderia cepacia |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
4.1.1.64 |
1-amino-1-cyclopropane carboxylate |
i.e. ACC |
Burkholderia cepacia |
|
4.1.1.64 |
5'-phosphopyridoxyl-2-methylalanine |
i.e. PPL-MeAla |
Burkholderia cepacia |
|
4.1.1.64 |
D-cycloserine |
competitive, L-isomer has 3000fold greater inhibitory potency than D-isomer |
Burkholderia cepacia |
|
4.1.1.64 |
L-Cycloserine |
competitive, L-isomer has 3000fold greater inhibitory potency than D-isomer |
Burkholderia cepacia |
|
4.1.1.64 |
phosphono-2-methylalanine |
- |
Burkholderia cepacia |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
4.1.1.64 |
Burkholderia cepacia |
P16932 |
- |
- |
Reaction
EC Number |
Reaction |
Comment |
Organism |
Reaction ID |
---|
4.1.1.64 |
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine |
mechanism |
Burkholderia cepacia |
|