Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Rigden, D.J.; Walter, R.A.; Phillips, S.E.; Fothergill-Gilmore, L.A.
    Polyanionic inhibitors of phosphoglycerate mutase: combined structural and biochemical analysis (1999), J. Mol. Biol., 289, 691-699.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.2.11 2,3-bisphosphoglycerate
-
 Schizosaccharomyces pombe
5.4.2.11 2,3-bisphosphoglycerate
-
 Saccharomyces cerevisiae

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.4.2.11 crystallization of PGAM complexed with inositol hexakisphosphate and benzene hexacarboxylate, crystal structures at 2.5-2.8 A resolution Saccharomyces cerevisiae

General Stability

EC Number General Stability Organism
5.4.2.11 little effect of the protease thermolysin on enzyme activity Schizosaccharomyces pombe

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.2.11 benzene hexacarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 benzene hexacarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 benzene-1,2,3-tricarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 benzene-1,2,3-tricarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 benzene-1,2,4,5-tetracarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 benzene-1,2,4,5-tetracarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 benzene-1,2,4-tricarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 benzene-1,2,4-tricarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 benzene-1,3,5-tricarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 benzene-1,3,5-tricarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 Inositol hexakisphosphate
-
 Saccharomyces cerevisiae
5.4.2.11 Inositol hexakisphosphate
-
 Schizosaccharomyces pombe

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4.2.11 0.56
-
 3-phosphoglycerate
-
 Saccharomyces cerevisiae
5.4.2.11 0.58
-
 3-phosphoglycerate
-
 Schizosaccharomyces pombe

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.2.11 2-phospho-D-glycerate Schizosaccharomyces pombe
-
 3-phospho-D-glycerate
-
 r
5.4.2.11 2-phospho-D-glycerate Saccharomyces cerevisiae
-
 3-phospho-D-glycerate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.11 Saccharomyces cerevisiae P00950
-
-
5.4.2.11 Schizosaccharomyces pombe
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.2.11
-
 Schizosaccharomyces pombe
5.4.2.11
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.11 2-phospho-D-glycerate
-
 Schizosaccharomyces pombe 3-phospho-D-glycerate
-
 r
5.4.2.11 2-phospho-D-glycerate
-
 Saccharomyces cerevisiae 3-phospho-D-glycerate
-
 r
5.4.2.11 3-Phosphoglycerate
-
 Schizosaccharomyces pombe 2-Phosphoglycerate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.2.11 PGAM
-
 Schizosaccharomyces pombe
5.4.2.11 PGAM
-
 Saccharomyces cerevisiae

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5.4.2.11 82
-
 3-phospho-D-glycerate
-
 Schizosaccharomyces pombe
5.4.2.11 530
-
 3-phosphoglycerate
-
 Saccharomyces cerevisiae

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
5.4.2.11 0.004
-
 Inositol hexakisphosphate
-
 Saccharomyces cerevisiae
5.4.2.11 0.006
-
 benzene hexacarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 0.013
-
 benzene-1,2,4,5-tetracarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 0.021
-
 benzene-1,2,4-tricarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 0.022
-
 benzene hexacarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 0.023
-
 benzene-1,2,3-tricarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 0.024
-
 benzene-1,3,5-tricarboxylate
-
 Saccharomyces cerevisiae
5.4.2.11 0.035
-
 Inositol hexakisphosphate
-
 Schizosaccharomyces pombe
5.4.2.11 0.053
-
 benzene-1,3,5-tricarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 0.055
-
 benzene-1,2,4,5-tetracarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 0.062
-
 benzene-1,2,4-tricarboxylate
-
 Schizosaccharomyces pombe
5.4.2.11 0.067
-
 benzene-1,2,3-tricarboxylate
-
 Schizosaccharomyces pombe