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Literature summary extracted from

  • Yoo, J.C.; Han, J.M.; Sohng, J.K.
    Expression of orf7(oxi III) as dTDP-glucose 4,6-dehydratase gene cloned from Streptomyces antibioticus Tu99 and biochemical characteristics of expressed protein (1999), J. Microbiol. Biotechnol., 9, 206-212.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.46 expression in Escherichia coli BL21 Streptomyces antibioticus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.46 dTDP
-
Streptomyces antibioticus
4.2.1.46 dTTP
-
Streptomyces antibioticus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.46 38000
-
2 * 38000, SDS-PAGE Streptomyces antibioticus

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.46 Streptomyces antibioticus
-
Tu99
-
4.2.1.46 Streptomyces antibioticus Tu99
-
Tu99
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.46 recombinant enzyme Streptomyces antibioticus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.46 dTDP-glucose
-
Streptomyces antibioticus dTDP-4-dehydro-6-deoxy-D-glucose + H2O
-
?
4.2.1.46 dTDP-glucose
-
Streptomyces antibioticus Tu99 dTDP-4-dehydro-6-deoxy-D-glucose + H2O
-
?

Subunits

EC Number Subunits Comment Organism
4.2.1.46 dimer 2 * 38000, SDS-PAGE Streptomyces antibioticus

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.1.46 NAD+ coenzyme is tightly bound to the protein Streptomyces antibioticus