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Literature summary extracted from

  • Steinberg, S.J.; Mihalik, S.J.; Kim, D.G.; Cuebas, D.A.; Watkins, P.A.
    The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate: CoA ligase (2000), J. Biol. Chem., 275, 15605-15608.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.2.1.7 expressed in COS-1 cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.7 endoplasmic reticulum
-
 Homo sapiens 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.7 ATP + cholate + CoA Homo sapiens re-activation and re-conjugation of bile acids AMP + diphosphate + choloyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.7 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.7 ATP + cholate + CoA
-
 Homo sapiens AMP + diphosphate + choloyl-CoA
-
 ?
6.2.1.7 ATP + cholate + CoA re-activation and re-conjugation of bile acids Homo sapiens AMP + diphosphate + choloyl-CoA
-
 ?
6.2.1.7 additional information enzyme additionally activates fatty acids Homo sapiens ?
-
 ?