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Literature summary extracted from

  • Park, S.J.; Cho, Y.D.
    Identification of functionally important residues of Arabidopsis thaliana S-adenosylmethionine decarboxylase (1999), J. Biochem., 126, 996-1003.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.50 C230A minimal effect on caqtalytic activity Arabidopsis thaliana
4.1.1.50 C50A minimal effect on caqtalytic activity Arabidopsis thaliana
4.1.1.50 C83A 10% residual enzymic activity Arabidopsis thaliana
4.1.1.50 K81A 60% residual enzymic activity, altered substrate specificity Arabidopsis thaliana

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.50 MDL73811 7% residual activity at 0.001 mM Arabidopsis thaliana
4.1.1.50 methylglyoxal bis-(guanylhydrazone)
-
 Arabidopsis thaliana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.50 0.023
-
 S-adenosyl-L-methionine
-
 Arabidopsis thaliana
4.1.1.50 1.518
-
 lysine
-
 Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.50 Arabidopsis thaliana Q96286
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.50 L-lysine
-
 Arabidopsis thaliana ?
-
 ?
4.1.1.50 S-adenosyl-L-methionine
-
 Arabidopsis thaliana (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.50 37
-
-
 Arabidopsis thaliana

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.50 7
-
-
 Arabidopsis thaliana

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.1.1.50 0.00015
-
 methylglyoxal bis-(guanylhydrazone)
-
 Arabidopsis thaliana