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Literature summary extracted from

  • Davis, M.S.; Cronan, J.E., Jr.
    Inhibition of Escherichia coli acetyl coenzyme A carboxylase by acyl-acyl carrier protein (2001), J. Bacteriol., 183, 1499-1503.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.4.1.2 Acyl carrier protein acylated derivatives, acyls with chain lengths from C6:0 to C20:1 are inhibitory, 0.04 mM results in 60-70% inhibition, complete inhibition not achieved even with very high concentrations Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.4.1.2 ATP + acetyl-CoA + HCO3- Escherichia coli key enzyme of fatty acid biosynthesis ADP + phosphate + malonyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.2 Escherichia coli
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-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.2 ATP + acetyl-CoA + HCO3-
-
 Escherichia coli ADP + phosphate + malonyl-CoA
-
 ?
6.4.1.2 ATP + acetyl-CoA + HCO3- key enzyme of fatty acid biosynthesis Escherichia coli ADP + phosphate + malonyl-CoA
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.2 biotin enzyme-bound Escherichia coli