EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.2.4 | D151N | reduced activity | Pseudomonas aeruginosa |
3.1.2.4 | E143A | no detectable activity | Pseudomonas aeruginosa |
3.1.2.4 | E143D | no detectable activity | Pseudomonas aeruginosa |
3.1.2.4 | E143Q | no detectable activity | Pseudomonas aeruginosa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.2.4 | Pseudomonas aeruginosa | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.1.2.4 | 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate | formation of an anhydride reaction intermediate, catalytic mechanism | Pseudomonas aeruginosa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.2.4 | 3-hydroxyisobutyryl-CoA + H2O | formation of an anhydride reaction intermediate, Glu164 is involved | Pseudomonas aeruginosa | CoA + 3-hydroxyisobutyrate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.2.4 | 3-hydroxyisobutyryl-CoA hydrolase | - |
Pseudomonas aeruginosa |
3.1.2.4 | HICH | - |
Pseudomonas aeruginosa |
3.1.2.4 | More | the enzyme belongs to the crotonase superfamily | Pseudomonas aeruginosa |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.2.4 | additional information | - |
additional information | - |
Pseudomonas aeruginosa | |
3.1.2.4 | 1 | - |
3-hydroxyisobutyryl-CoA | mutant D151N | Pseudomonas aeruginosa | |
3.1.2.4 | 89 | - |
3-hydroxyisobutyryl-CoA | wild-type enzyme, a deuterium isotope of the substrate is used | Pseudomonas aeruginosa |