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Literature summary extracted from

  • Gao, J.R.; Zhu, K.Y.
    An acetylcholinesterase purified from the greenbug (Schizaphis graminum) with some unique enzymological and pharmacological characteristics (2001), Insect Biochem. Mol. Biol., 31, 1095-1104.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide i.e. BW284c51, 98% inhibition at 0.01 mM Schizaphis graminum
3.1.1.7 eserine 98% inhibition at 0.01 mM Schizaphis graminum
3.1.1.7 ethopropazine 7% inhibition at 0.01 mM Schizaphis graminum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.7 0.031
-
 propionylthiocholine
-
 Schizaphis graminum
3.1.1.7 0.0334
-
 S-butyrylthiocholine
-
 Schizaphis graminum
3.1.1.7 0.0576
-
 acetylthiocholine
-
 Schizaphis graminum
3.1.1.7 0.061
-
 acetyl-(beta-methyl)thiocholine
-
 Schizaphis graminum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.7 72000
-
 x * 72000, SDS-PAGE Schizaphis graminum
3.1.1.7 129000
-
 gel filtration Schizaphis graminum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.7 acetylcholine + H2O Schizaphis graminum
-
 choline + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Schizaphis graminum
-
 greenbug
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetyl-(beta-methyl)thiocholine + H2O
-
 Schizaphis graminum (beta-methyl)thiocholine + acetate
-
 ?
3.1.1.7 acetylcholine + H2O
-
 Schizaphis graminum choline + acetate
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Schizaphis graminum thiocholine + acetate
-
 ?
3.1.1.7 propionylthiocholine + H2O
-
 Schizaphis graminum thiocholine + propionate
-
 ?
3.1.1.7 S-butyrylthiocholine + H2O
-
 Schizaphis graminum thiocholine + butyrate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.7 ? x * 72000, SDS-PAGE Schizaphis graminum

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.1.1.7 Schizaphis graminum three isoforms: 1 major form with pI 7.3 and 2 minor forms with pI 6.3 and pI 7.1, isoelectric focusing 6.8 6.3
3.1.1.7 Schizaphis graminum three isoforms: 1 major form with pI 7.3 and 2 minor forms with pI 6.3 and pI 7.1, isoelectric focusing
-
 7.1
3.1.1.7 Schizaphis graminum three isoforms: 1 major form with pI 7.3 and 2 minor forms with pI 6.3 and pI 7.1, isoelectric focusing 7.4 7.3