Any feedback?
Literature summary extracted from
- DNase II: genes, enzymes and function (2003), Gene, 322, 1-15.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.22.1 | - |
Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.22.1 | lysosome | - |
Homo sapiens | 5764 | - |
| 3.1.22.1 | lysosome | - |
Caenorhabditis elegans | 5764 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.22.1 | additional information | Caenorhabditis elegans | The enzyme plays a role in the degradation of exogenous DNA encountered by phagocytosis and is important for DNA fragmentation and degradation during cell death | ? | - |
? |  |
| 3.1.22.1 | additional information | Caenorhabditis elegans NUC-1 | The enzyme plays a role in the degradation of exogenous DNA encountered by phagocytosis and is important for DNA fragmentation and degradation during cell death | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.22.1 | Caenorhabditis elegans | - |
NUC-1 | - |
| 3.1.22.1 | Caenorhabditis elegans NUC-1 | - |
NUC-1 | - |
| 3.1.22.1 | Drosophila melanogaster | - |
- |
- |
| 3.1.22.1 | Homo sapiens | - |
- |
- |
| 3.1.22.1 | Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.22.1 | DNA + H2O | - |
Homo sapiens | 3'-phosphooligonucleotides + 5'-hydroxyoligonucleotides | - |
? | |
| 3.1.22.1 | additional information | The enzyme plays a role in the degradation of exogenous DNA encountered by phagocytosis and is important for DNA fragmentation and degradation during cell death | Caenorhabditis elegans | ? | - |
? | |
| 3.1.22.1 | additional information | The enzyme plays a role in the degradation of exogenous DNA encountered by phagocytosis and is important for DNA fragmentation and degradation during cell death | Caenorhabditis elegans NUC-1 | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.22.1 | DNase II homolog | - |
Caenorhabditis elegans |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
