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Literature summary extracted from

  • Schrick, J.J.; Lingrel, J.B.
    cDNA cloning, mapping and expression of the mouse propionyl CoA carboxylase beta (pccb), the gene for human type II propionic acidaemia (2001), Gene, 264, 147-152.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.4.1.3 mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.4.1.3 ATP + propanoyl-CoA + HCO3- Homo sapiens key enzyme in catabolic pathways for odd-chain fatty acids and branched chain amino acids ADP + phosphate + (S)-methylmalonyl-CoA
-
 ?
6.4.1.3 ATP + propanoyl-CoA + HCO3- Mus musculus key enzyme in catabolic pathways for odd-chain fatty acids and branched chain amino acids ADP + phosphate + (S)-methylmalonyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.3 Homo sapiens
-
-
-
6.4.1.3 Mus musculus Q99MN9 cDNA of the beta subunit; studies on beta subunit
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.3 ATP + propanoyl-CoA + HCO3-
-
 Homo sapiens ADP + phosphate + (S)-methylmalonyl-CoA
-
 ?
6.4.1.3 ATP + propanoyl-CoA + HCO3-
-
 Mus musculus ADP + phosphate + (S)-methylmalonyl-CoA
-
 ?
6.4.1.3 ATP + propanoyl-CoA + HCO3- key enzyme in catabolic pathways for odd-chain fatty acids and branched chain amino acids Homo sapiens ADP + phosphate + (S)-methylmalonyl-CoA
-
 ?
6.4.1.3 ATP + propanoyl-CoA + HCO3- key enzyme in catabolic pathways for odd-chain fatty acids and branched chain amino acids Mus musculus ADP + phosphate + (S)-methylmalonyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
6.4.1.3 dodecamer 6 * alpha + 6 * beta Homo sapiens
6.4.1.3 dodecamer 6 * alpha + 6 * beta Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.3 biotin bound to enzyme Homo sapiens
6.4.1.3 biotin bound to enzyme Mus musculus