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Literature summary extracted from

  • Bollen, M.; Gijsbers, R.; Ceulemans, H.; Stalmans, W.; Stefan, C.
    Nucleotide pyrophosphatases/phosphodiesterases on the move (2000), Crit. Rev. Biochem. Mol. Biol., 35, 393-432.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.1 additional information overview on subcellular localization Mammalia
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.1 additional information Mammalia implication of enzyme in intra- and extracellular processes, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.1 Mammalia
-
 isozymes NPP1, Npp2, NPP3
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Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.4.1 glycoprotein NPP2, NPP3 Mammalia

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.4.1 hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides mechanism, overview Mammalia
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.1 additional information overview on tissue distribution Mammalia
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.1 additional information overview on substrate specificity Mammalia ?
-
 ?
3.1.4.1 additional information implication of enzyme in intra- and extracellular processes, overview Mammalia ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.4.1 dimer NPP1, NPP2, NPP3, disulfide-linked homodimers, overview Mammalia
3.1.4.1 additional information consists of a short N-terminal intracellular domain, a single transmembrane domain, two somatomedin-B-like domains, a catalytic domain and a C-terminal nuclease-like domain, overview Mammalia

Synonyms

EC Number Synonyms Comment Organism
3.1.4.1 autotaxin
-
 Mammalia
3.1.4.1 B10
-
 Mammalia
3.1.4.1 gp130RB13-6
-
 Mammalia
3.1.4.1 additional information overview on nomenclature and synonyms Mammalia