EC Number | Crystallization (Comment) | Organism |
---|---|---|
3.1.1.7 | complexed with (-)-huperzine B and (+)-huperzine A | Tetronarce californica |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.7 | (+)-huperzine A | synthetic enantiomer of the anti-Alzheimer drug (-)-huperzine A and of its natural homologue (-)-huperzine B, interacts with the anionic subsite of the active site | Tetronarce californica | |
3.1.1.7 | (-)-huperzine A | anti-Alzheimer drug | Tetronarce californica | |
3.1.1.7 | (-)-huperzine B | - |
Tetronarce californica |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.7 | Tetronarce californica | P04058 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.7 | acetylcholine + H2O | - |
Tetronarce californica | choline + acetate | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.7 | 0.175 | - |
(-)-huperzine A | pH 7, 25°C | Tetronarce californica | |
3.1.1.7 | 0.334 | - |
(-)-huperzine B | pH 7, 25°C | Tetronarce californica | |
3.1.1.7 | 4.3 | - |
(+)-huperzine A | pH 7, 25°C | Tetronarce californica |