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Literature summary extracted from
- Single-turnover kinetic analysis of Trypanosoma cruzi S-adenosylmethionine decarboxylase (2000), Biochemistry, 39, 3336-3343.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 4.1.1.50 | C82A | drastically reduced single turnover rate, no solvent isotope effect, C82 may function as a general aci/base in catalysis | Trypanosoma cruzi |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.50 | Trypanosoma cruzi | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 4.1.1.50 | S-adenosyl-L-methionine = S-adenosyl 3-(methylsulfanyl)propylamine + CO2 | kinetic analysis, inverse solvent isotope effect | Trypanosoma cruzi |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.50 | S-adenosyl-L-methionine | - |
Trypanosoma cruzi | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2 | - |
? |  |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.50 | 6 | - |
S-adenosyl-methionine | in presence of putrescine | Trypanosoma cruzi | |
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Release 2023.1 (January 2023)
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