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Literature summary extracted from

  • Meyer, E.; Kappock, T.J.; Osuji, C.; Stubbe, J.
    Evidence for the Direct Transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase (1999), Biochemistry, 38, 3012-3018.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.6 ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate Escherichia coli
-
 ADP + phosphate + (S)-2-[5-amino1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.18 Escherichia coli
-
-
-
6.3.2.6 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.18 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole the carbamate carboxylate is directly transferred to generate 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate, without equilibration with HCO3- and CO2 in solution Escherichia coli 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
-
 ?
6.3.2.6 ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate
-
 Escherichia coli ADP + phosphate + (S)-2-[5-amino1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.99.18 PurE
-
 Escherichia coli
6.3.2.6 PurC
-
 Escherichia coli
6.3.2.6 SAICAR synthetase
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 Escherichia coli