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Literature summary extracted from

  • Yoshimura, M.; Nakano, Y.; Koga, T.
    L-Methionine-gamma-lyase, as a target to inhibit malodorous bacterial growth by trifluoromethionine (2002), Biochem. Biophys. Res. Commun., 292, 964-968.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.11 cloning of mgl gene Porphyromonas gingivalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.11 L-methionine + H2O Porphyromonas gingivalis
-
methanethiol + NH3 + 2-oxobutanoate
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.11 Porphyromonas gingivalis
-
black-pigmented anaerobe strongly implicated as a major pathogen in adult periodontitis, growth of Porphyromonas gingivalis is inhibited by L-trifluoromethionine
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.11 L-methionine + H2O
-
Porphyromonas gingivalis methanethiol + NH3 + 2-oxobutanoate
-
?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.11 L-methionine-alpha-deamino-gamma-mercaptomethane-lyase
-
Porphyromonas gingivalis
4.4.1.11 METase
-
Porphyromonas gingivalis

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.11 pyridoxal 5'-phosphate
-
Porphyromonas gingivalis