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Literature summary extracted from

  • Bracher, D.; Kutchan, T.M.
    Strictosidine synthase from Rauvolfia serpentina: analysis of a gene involved in indole alkaloid biosynthesis (1992), Arch. Biochem. Biophys., 294, 717-723.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.99.13
-
 Rauvolfia mannii
3.5.99.13 expressed in Nicotiana plumbaginifolia cultured cells Rauvolfia serpentina

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.99.13 tryptamine + secologanin Rauvolfia serpentina involved in synthesis of monoterpenoid indole alkaloides 3-alpha(S)-strictosidine + H2O
-
 ?
3.5.99.13 tryptamine + secologanin Rauvolfia mannii involved in synthesis of monoterpenoid indole alkaloides 3-alpha(S)-strictosidine + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.99.13 Rauvolfia mannii
-
-
-
3.5.99.13 Rauvolfia serpentina
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.99.13 flower low activity Rauvolfia serpentina
-
3.5.99.13 leaf
-
 Rauvolfia serpentina
-
3.5.99.13 root
-
 Rauvolfia serpentina
-
3.5.99.13 stem low activity Rauvolfia serpentina
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.99.13 tryptamine + secologanin
-
 Rauvolfia serpentina 3-alpha(S)-strictosidine + H2O
-
 ?
3.5.99.13 tryptamine + secologanin
-
 Rauvolfia mannii 3-alpha(S)-strictosidine + H2O
-
 ?
3.5.99.13 tryptamine + secologanin involved in synthesis of monoterpenoid indole alkaloides Rauvolfia serpentina 3-alpha(S)-strictosidine + H2O
-
 ?
3.5.99.13 tryptamine + secologanin involved in synthesis of monoterpenoid indole alkaloides Rauvolfia mannii 3-alpha(S)-strictosidine + H2O
-
 ?