EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.10 | 2,3-cyclopropylgeranyl diphosphate | competitive inhibitor | Anethum foeniculum | |
4.2.3.10 | 2-Fluorogeranyl diphosphate | effective competitive inhibitor | Anethum foeniculum | |
4.2.3.10 | 2-fluorolinalyl diphosphate | effective competitive inhibitor | Anethum foeniculum | |
4.2.3.10 | 6,7-dihydrogeranyl diphosphate | competitive inhibitor | Anethum foeniculum | |
4.2.3.10 | additional information | synergistic effect of sulfonium analog inorganic diphosphate combinations in the inhibition of fenchol cyclase | Anethum foeniculum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.3.10 | 0.006 | - |
geranyl diphosphate | - |
Anethum foeniculum | |
4.2.3.10 | 0.02 | - |
2,3-cyclopropylgeranyl diphosphate | pH 6.5, 30°C | Anethum foeniculum | |
4.2.3.10 | 0.025 | - |
6,7-dihydrogeranyl diphosphate | pH 6.5, 30°C | Anethum foeniculum |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.10 | Mn2+ | Mn2+-dependent formation of ether-soluble products from 6,7-dihydrogeranyl diphosphate | Anethum foeniculum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.10 | geranyl diphosphate | Anethum foeniculum | - |
(-)-endo-fenchol + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.3.10 | Anethum foeniculum | - |
M. var. vulgare | - |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
4.2.3.10 | geranyl diphosphate + H2O = (-)-endo-fenchol + diphosphate | reaction mechanism | Anethum foeniculum | |
4.2.3.10 | geranyl diphosphate + H2O = (-)-endo-fenchol + diphosphate | (3R)-linalyl diphosphate is an intermediate in the reaction | Anethum foeniculum |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.2.3.10 | leaf | young emerging leaves from 30-day-old plants | Anethum foeniculum | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.10 | 2,3-cyclopropylgeranyl diphosphate | at 53% of the rate of conversion of geranyl diphosphate, formation of ether-soluble products | Anethum foeniculum | ? | - |
? | |
4.2.3.10 | 6,7-dihydrogeranyl diphosphate | at 35% of the rate of conversion of geranyl diphosphate, formation of ether-soluble products | Anethum foeniculum | ? | - |
? | |
4.2.3.10 | dimethylallyl diphosphate | at the same rate as the cyclization of geranyl diphosphate | Anethum foeniculum | dimethylallyl alcohol + diphosphate | - |
? | |
4.2.3.10 | farnesyl diphosphate | at 25% of the rate of conversion of geranyl diphosphate, formation of ether-soluble products | Anethum foeniculum | ? | - |
? | |
4.2.3.10 | geranyl diphosphate | - |
Anethum foeniculum | (-)-endo-fenchol + diphosphate | - |
? | |
4.2.3.10 | geranyl diphosphate | mechanism of the isomerization-cyclization reaction | Anethum foeniculum | (-)-endo-fenchol + diphosphate | - |
? | |
4.2.3.10 | geranyl diphosphate | (3R)-linalyl diphosphate is an intermediate in the reaction | Anethum foeniculum | (-)-endo-fenchol + diphosphate | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
4.2.3.10 | 30 | - |
assay at | Anethum foeniculum |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.3.10 | 6.5 | - |
assay at | Anethum foeniculum |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.3.10 | additional information | - |
additional information | - |
Anethum foeniculum | |
4.2.3.10 | 0.01 | - |
2-Fluorogeranyl diphosphate | pH 6.5, 30°C | Anethum foeniculum | |
4.2.3.10 | 0.013 | - |
2-fluorolinalyl diphosphate | pH 6.5, 30°C | Anethum foeniculum | |
4.2.3.10 | 0.035 | - |
2,3-cyclopropylgeranyl diphosphate | pH 6.5, 30°C | Anethum foeniculum | |
4.2.3.10 | 0.04 | - |
6,7-dihydrogeranyl diphosphate | pH 6.5, 30°C | Anethum foeniculum |