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Literature summary extracted from
- Glucosaminephosphate isomerase from house flies (1975), Methods Enzymol., 41B, 400-407.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.99.6 | 2-deoxyglucose 6-phosphate | activates | Musca domestica |  |
| 3.5.99.6 | 6-phosphogluconate | activates | Musca domestica | |
| 3.5.99.6 | D-glucose 6-phosphate | activates | Musca domestica | |
| 3.5.99.6 | D-mannose 6-phosphate | - |
Musca domestica | |
| 3.5.99.6 | N-acetylglucosamine 6-phosphate | activates | Musca domestica | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.99.6 | phosphate | slight inhibition | Musca domestica | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.99.6 | 4.2 | - |
NH4+ | pH 8.5, 37°C, in presence of glucose 6-phosphate | Musca domestica | |
| 3.5.99.6 | 4.8 | - |
D-fructose 6-phosphate | pH 8.5, 37°C, in presence of 10 mM glucose 6-phosphate | Musca domestica | |
| 3.5.99.6 | 17 | - |
D-glucosamine 6-phosphate | pH 8.5, 37°C, in absence of activators, or in presence of glucose 6-phosphate | Musca domestica | |
| 3.5.99.6 | 36 | - |
D-fructose 6-phosphate | pH 8.5, 37°C, in absence of activators | Musca domestica | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.99.6 | arsenate | activates | Musca domestica | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.5.99.6 | 154000 | - |
sucrose density gradient centrifugation | Musca domestica |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.99.6 | Musca domestica | - |
- |
- |
| 3.5.99.6 | Sarcophaga bullata | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.99.6 | - |
Musca domestica |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.5.99.6 | pupa | - |
Musca domestica | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.99.6 | D-glucosamine 6-phosphate + H2O | - |
Sarcophaga bullata | D-fructose 6-phosphate + NH3 | - |
? | |
| 3.5.99.6 | D-glucosamine 6-phosphate + H2O | - |
Musca domestica | D-fructose 6-phosphate + NH3 | - |
r | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.5.99.6 | 7.1 | 7.3 | in absence of activators | Musca domestica |
| 3.5.99.6 | 8.2 | 8.4 | in presence of phosphate and D-glucose 6-phosphate | Musca domestica |
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Release 2023.1 (January 2023)
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