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Literature summary extracted from
- Activation of tubulinyl-tyrosine carboxypeptidase by spermine, spermidine and putrescine (1982), Biochem. Biophys. Res. Commun., 108, 654-657.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.17 | putrescine | maximal stimulation at 6 mM | Gallus gallus |  |
| 3.4.17.17 | spermidine | stimulates, maximal stimulation at 1 mM, inhibition above | Gallus gallus | |
| 3.4.17.17 | spermine | maximal stimulation at 0.06 mM | Gallus gallus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.17 | putrescine | inhibition above 6 mM | Gallus gallus | |
| 3.4.17.17 | spermidine | inhibition above 1 mM | Gallus gallus | |
| 3.4.17.17 | spermine | above 0.06 mM | Gallus gallus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.17 | Mg2+ | activates, maximal activation at 4-6 mM | Gallus gallus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.17.17 | Gallus gallus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.17.17 | brain | - |
Gallus gallus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.17.17 | tyrosinated tubulin + H2O | - |
Gallus gallus | tubulin + Tyr | - |
? | |
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Release 2023.1 (January 2023)
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