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Literature summary extracted from

  • La Du, B.N.; Adkins, S.; Kuo, C.L.; Lipsig, D.
    Studies on human serum paraoxonase/arylesterase (1993), Chem. Biol. Interact., 87, 25-34.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.2 1,2-dilauroyl-phosphatidylcholine stimulation Homo sapiens
3.1.1.2 dioleoyl phosphatidylcholine stimulation Homo sapiens
3.1.1.2 lecithin stimulation Homo sapiens
3.1.1.2 lysolecithin stimulation Homo sapiens
3.1.1.2 phosphatidylcholine purified A or B-type esterases are stimulated Homo sapiens
3.1.1.2 phosphatidylethanolamine stimulation Homo sapiens
3.1.1.2 phosphatidylglycerol stimulation Homo sapiens
3.1.8.1 dilauroyl phosphatidylcholine stimulation Homo sapiens
3.1.8.1 dioleoyl phosphatidylcholine stimulation Homo sapiens
3.1.8.1 lecithin stimulation Homo sapiens
3.1.8.1 lysolecithin stimulation Homo sapiens
3.1.8.1 phosphatidylcholine purified A or B-type esterases are stimulated Homo sapiens
3.1.8.1 phosphatidylethanolamine stimulation Homo sapiens
3.1.8.1 phosphatidylglycerol stimulation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.2 6-palmityl-ascorbic acid
-
 Homo sapiens
3.1.1.2 phosphatidylserine
-
 Homo sapiens
3.1.8.1 6-palmityl-ascorbic acid
-
 Homo sapiens
3.1.8.1 phosphatidylserine
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.2 NaCl B-type esterase has relatively higher paraoxonase activity and is stimulated to a greater degree by 1 M NaCl than the A allozyme Homo sapiens
3.1.8.1 NaCl B-type esterase has relatively higher paraoxonase activity and is stimulated to a greater degree by 1 M NaCl than the A allozyme Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.2 Homo sapiens
-
-
-
3.1.8.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.2 blood serum in serum, the esterase is tightly bound to the high density lipoproteins, particularly apo A-l Homo sapiens
-
3.1.8.1 blood serum in serum, the esterase is tightly bound to the high density lipoproteins, particularly apo A-l Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.2 phenyl acetate + H2O the enzyme exists in two genetically determined allozymic forms, and these A and B allozymes possess both paraoxonase and arylesterase activities. B-type esterase has relatively higher paraoxonase activity and is stimulated to a greater degree by 1 M NaCl than the A allozyme Homo sapiens phenol + acetate
-
 ?
3.1.8.1 paraoxon + H2O the enzyme exists in two genetically determined allozymic forms, and these A and B allozymes possess both paraoxonase and arylesterase activities. B-type esterase has relatively higher paraoxonase activity and is stimulated to a greater degree by 1 M NaCl than the A allozyme Homo sapiens diethylphosphate + 4-nitrophenol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.2 paraoxonase/arylesterase
-
 Homo sapiens