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Literature summary extracted from

  • Sanjanwala, M.; Sun, G.Y.; MacQuarrie, R.A.
    Purification of long-chain acyl-CoA hydrolase from bovine heart microsomes and regulation of activity by lysophospholipids (1987), Arch. Biochem. Biophys., 258, 299-306.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.2.2 acetyl-CoA
-
 Bos taurus
3.1.2.2 Ca2+ weakly inhibitory Bos taurus
3.1.2.2 lysophosphatidylcholine strongly inhibitory Bos taurus
3.1.2.2 lysophosphatidylethanolamine weakly inhibitory Bos taurus
3.1.2.2 lysophosphatidylinositol strong inhibition Bos taurus
3.1.2.2 lysophosphatidylserine weakly inhibitory Bos taurus
3.1.2.2 Mg2+ weak inhibition Bos taurus
3.1.2.2 Mn2+ weakly inhibitory Bos taurus
3.1.2.2 sodium deoxycholate
-
 Bos taurus
3.1.2.2 Triton X-100
-
 Bos taurus
3.1.2.20 acetyl-CoA
-
 Bos taurus
3.1.2.20 Ca2+ weakly inhibitory Bos taurus
3.1.2.20 lysophosphatidylcholine strongly inhibitory Bos taurus
3.1.2.20 lysophosphatidylethanolamine weakly inhibitory Bos taurus
3.1.2.20 lysophosphatidylinositol strong inhibition Bos taurus
3.1.2.20 lysophosphatidylserine weakly inhibitory Bos taurus
3.1.2.20 Mg2+ weak inhibition Bos taurus
3.1.2.20 Mn2+ weakly inhibitory Bos taurus
3.1.2.20 sodium deoxycholate
-
 Bos taurus
3.1.2.20 Triton X-100
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.2.2 0.0004
-
 Arachidonoyl-CoA
-
 Bos taurus
3.1.2.2 0.0026
-
 oleoyl-CoA
-
 Bos taurus
3.1.2.20 0.0004
-
 Arachidonoyl-CoA
-
 Bos taurus
3.1.2.20 0.0026
-
 oleoyl-CoA
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.2 microsome
-
 Bos taurus
-
-
3.1.2.20 microsome
-
 Bos taurus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.2.2 40000
-
 x * 40000, SDS-PAGE Bos taurus
3.1.2.2 41000
-
 x * 41000, SDS-PAGE Bos taurus
3.1.2.20 40000
-
 x * 40000, SDS-PAGE Bos taurus
3.1.2.20 41000
-
 x * 41000, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.2 Bos taurus
-
-
-
3.1.2.20 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.2.2
-
 Bos taurus
3.1.2.20
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.2 heart
-
 Bos taurus
-
3.1.2.20 heart
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.2.2 6
-
-
 Bos taurus
3.1.2.20 6
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.2 arachidonoyl-CoA + H2O most effective substrate Bos taurus CoA + arachidonate
-
 ?
3.1.2.2 oleoyl-CoA + H2O
-
 Bos taurus CoA + oleate
-
 ?
3.1.2.20 arachidonoyl-CoA + H2O most effective substrate Bos taurus CoA + arachidonate
-
 ?
3.1.2.20 oleoyl-CoA + H2O
-
 Bos taurus CoA + oleate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.2.2 ? x * 40000, SDS-PAGE Bos taurus
3.1.2.2 ? x * 41000, SDS-PAGE Bos taurus
3.1.2.20 ? x * 40000, SDS-PAGE Bos taurus
3.1.2.20 ? x * 41000, SDS-PAGE Bos taurus