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Literature summary extracted from

  • Saxl, R.L.; Anand, G.S.; Stock, A.M.
    Synthesis and Biochemical Characterization of a Phosphorylated Analogue of the Response Regulator CheB (2001), Biochemistry, 40, 12896-12903.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.1.1.61 C207S/C309S wild-type and mutant enzyme show significantly greater activity than the unphosphorylated proteins Salmonella enterica subsp. enterica serovar Typhimurium
3.1.1.61 D56C/C207S/C309S the half-life of mutant-SPO3 is 28 days, the unphosphorylated wild-type and mutant enzyme show the same enzyme activities Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.61 Salmonella enterica subsp. enterica serovar Typhimurium
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-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.61 phosphoprotein enzyme is activated in vivo by phosphorylation of a single aspartate, Asp56, in its regulatory domain Salmonella enterica subsp. enterica serovar Typhimurium

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.1.61 protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol the enzyme is a response regulator protein in the bacterial chemotaxis two-component signal transduction pathway Salmonella enterica subsp. enterica serovar Typhimurium

Subunits

EC Number Subunits Comment Organism
3.1.1.61 More the CheB protein is composed of at least 2 structurally distinct proportions: a C-terminal catalytic domain, and a N-terminal region which modulates esterase activity Salmonella enterica subsp. enterica serovar Typhimurium