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Literature summary extracted from

  • White, K.N.; Vale, V.L.; Hope, D.B.
    Identification of common forms of salicylate esterases in guinea-pig tissues similar to the microsomal aspirinases of liver (1994), Biochem. Soc. Trans., 22, 220S.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.55 bis(4-nitrophenyl)hydrogen phosphate i.e. BNPP, organophosphate carboxylesterase inhibitor, enzymes from intestinal and gastric mucosa are inhibited by 80% at 0.1 mM, while the liver enzyme shows only 25% inhibition Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.55 cytosol
-
 Cavia porcellus 5829
-
3.1.1.55 microsome
-
 Cavia porcellus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.55 acetyl salicylate + H2O Cavia porcellus i.e. aspirin salicylate + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.55 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.55 gastric mucosa cytosol Cavia porcellus
-
3.1.1.55 intestinal mucosa
-
 Cavia porcellus
-
3.1.1.55 kidney
-
 Cavia porcellus
-
3.1.1.55 liver
-
 Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.55 acetyl salicylate + H2O i.e. aspirin Cavia porcellus salicylate + acetate
-
 ?
3.1.1.55 acetylsalicylate + H2O i.e. aspirin Cavia porcellus salicylate + acetate
-
 ?