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Literature summary extracted from

  • Pai, T.G.; Suiko, M.; Sakakibara, Y.; Liu, M.C.
    Sulfation of Flavonoids and Other Phenolic Dietary Compounds by the Human Cytosolic Sulfotransferases (2001), Biochem. Biophys. Res. Commun., 285, 1175-1179.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.8.2.4 medicine development of flavonoid, isoflavonoid and phenolic inhibitors of the bioactivation of carcinogens by the enzyme Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.4 SULT1E1 cloned and expressed in Escherichia coli BL21 (DE3) Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.4 cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.4 3'-phosphoadenylylsulfate + estrone Homo sapiens
-
 adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.4 Homo sapiens P49888 human
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.4 0.000158
-
 catechin hydrate as substrate Homo sapiens
2.8.2.4 0.000171
-
 daidzein as substrate Homo sapiens
2.8.2.4 0.000193
-
 genistein as substrate Homo sapiens
2.8.2.4 0.000343
-
 epigallocatechin gallate as substrate Homo sapiens
2.8.2.4 0.000351
-
 epicatechin as substrate Homo sapiens
2.8.2.4 0.000393
-
 butylated hydroxyanisole as substrate Homo sapiens
2.8.2.4 0.000452
-
 kaempferol as substrate Homo sapiens
2.8.2.4 0.000505
-
 17alpha-ethynylestradiol as substrate Homo sapiens
2.8.2.4 0.000526
-
 estrone as substrate Homo sapiens
2.8.2.4 0.000594
-
 myricetin as substrate Homo sapiens
2.8.2.4 0.000597
-
 n-propyl gallate as substrate Homo sapiens
2.8.2.4 0.00061
-
 quercetin as substrate Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.4 3'-phosphoadenylylsulfate + 17alpha ethinyl estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 17alpha ethinyl estradiol 3-sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + butylated hydroxyanisole
-
 Homo sapiens adenosine 3',5'-bisphosphate + butylated hydroxyanisole sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + catechin hydrate
-
 Homo sapiens adenosine 3',5'-bisphosphate + catechin hydrate sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + daidzein
-
 Homo sapiens adenosine 3',5'-bisphosphate + daidzein sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + epicatechin
-
 Homo sapiens adenosine 3',5'-bisphosphate + epicatechin sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + epigallocatechin gallate
-
 Homo sapiens adenosine 3',5'-bisphosphate + epigallocatechin gallate sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + estrone
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + genistein
-
 Homo sapiens adenosine 3',5'-bisphosphate + genistein 7-sulfate + genistein 4'-sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + kaempferol
-
 Homo sapiens adenosine 3',5'-bisphosphate + kaempferol sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + myricetin
-
 Homo sapiens adenosine 3',5'-bisphosphate + myricetin sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + n-propyl gallate
-
 Homo sapiens adenosine 3',5'-bisphosphate + n-propyl gallate sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + quercetin
-
 Homo sapiens adenosine 3',5'-bisphosphate + quercetin sulfate
-
 r
2.8.2.4 additional information caffeic acid, chlorogenic acid, BHT, and gallic acid are no substrates Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.4 SULT1E1
-
 Homo sapiens