EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.8.1.6 | S-adenosyl-L-methionine | one molecule S-adenosyl-L-methionine is required to form one molecule of biotin | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.1.6 | 5'-deoxyadenosine | strong inhibitor, reversible, 90% inhibition upon addition of 1 equivalent of 5'-deoxyadenosine with regard to the enzyme | Escherichia coli |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.8.1.6 | Iron | the enzyme contains an iron-sulfur cluster | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur | Escherichia coli | catalyzes the last step of the biosynthesis of biotin | biotin | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.1.6 | Escherichia coli | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur | - |
Escherichia coli | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | catalyzes the last step of the biosynthesis of biotin | Escherichia coli | biotin | - |
? |